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Clinical Trials/NCT00605124
NCT00605124
Completed
Not Applicable

Progressive Exercise After Total Knee Arthroplasty: A Randomised Controlled Trial

Jyväskylä Central Hospital1 site in 1 country120 target enrollmentJanuary 2008
ConditionsOsteoarthritis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Osteoarthritis
Sponsor
Jyväskylä Central Hospital
Enrollment
120
Locations
1
Primary Endpoint
Functional tests, pain
Status
Completed
Last Updated
13 years ago

Overview

Brief Summary

Total knee arthroplasty (TKA) is performed more than 7.000 times a year in Finland most often for osteoarthritis (OA). While pain is predictably reduced, function does not typically ever reach that of age-matched, uninjured subjects. Quadriceps weakness has been implicated in the development and progression of knee OA and is a significant problem after TKA. Advance to return to normal daily activities is not sufficient to restore knee function or quadriceps strength after TKA.

The aim of this study is to assess the effectiveness of progressive exercise program restoring knee strength, mobility and improving the functional outcome after primary TKA.

Detailed Description

Many studies have shown, that after TKA pain decreased significantly, but muscle strength of the operated knee did not recover and may stay under the preoperative level. To find out the effects of progressive exercise program the investigators will perform, 6 weeks after TKA, a randomized clinical trial of lower extremity strength training using two subgroups of people: traditional exercise group and progressive exercise group.

Registry
clinicaltrials.gov
Start Date
January 2008
End Date
December 2012
Last Updated
13 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Jyväskylä Central Hospital
Responsible Party
Principal Investigator
Principal Investigator

Mirja Vuorenmaa

physiotherapist

Jyväskylä Central Hospital

Eligibility Criteria

Inclusion Criteria

  • primary unilateral TKA for knee osteoarthritis

Exclusion Criteria

  • Rheumatoid arthritis
  • Fibromyalgia
  • Bilateral TKA
  • Heart or lung disease, which prevent training
  • Unstable serious disease (cancer)
  • Reduced cooperation (drug, alcohol abuse, mental illness)

Outcomes

Primary Outcomes

Functional tests, pain

Time Frame: baseline , 6 weeks after operation (start of training), after 12 months training

Timed-Up and Go-test, Visual analogue scale (VAS)

Secondary Outcomes

  • Knee muscle strength(baseline, 6 weeks after operation (start of training), after 12 months training)
  • Health related quality of life(baseline and 12 months)
  • gait analysis(baseline, 6 weeks postoperatively, 12 months)

Study Sites (1)

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