Progressive Exercise After Total Knee Arthroplasty (TKA)

Not Applicable

Completed

• Conditions: Osteoarthritis
• Interventions: Other: Knee muscle exercises

• Registration Number: NCT00605124
• Lead Sponsor: Jyväskylä Central Hospital

Brief Summary

Total knee arthroplasty (TKA) is performed more than 7.000 times a year in Finland most often for osteoarthritis (OA). While pain is predictably reduced, function does not typically ever reach that of age-matched, uninjured subjects. Quadriceps weakness has been implicated in the development and progression of knee OA and is a significant problem after TKA. Advance to return to normal daily activities is not sufficient to restore knee function or quadriceps strength after TKA.

The aim of this study is to assess the effectiveness of progressive exercise program restoring knee strength, mobility and improving the functional outcome after primary TKA.

Detailed Description

Many studies have shown, that after TKA pain decreased significantly, but muscle strength of the operated knee did not recover and may stay under the preoperative level. To find out the effects of progressive exercise program the investigators will perform, 6 weeks after TKA, a randomized clinical trial of lower extremity strength training using two subgroups of people: traditional exercise group and progressive exercise group.

Study Timeline

• Study Start: 2008-01
• Study First Submitted: 2008-01-16
• Study First Submitted QC: 2008-01-16
• Study First Posted: 2008-01-30
• Primary Completion: 2010-12
• Study Completion: 2012-12
• Status Verified: 2013-03
• Last Update Submitted: 2013-03-04
• Last Update Posted: 2013-03-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• primary unilateral TKA for knee osteoarthritis

Exclusion Criteria

• Rheumatoid arthritis
• Fibromyalgia
• Bilateral TKA
• Heart or lung disease, which prevent training
• Unstable serious disease (cancer)
• Reduced cooperation (drug, alcohol abuse, mental illness)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
exercise	Knee muscle exercises	progressive exercise, home-based exercise program, tree exercise sessions weekly, chec-up visits every third month
Conventional treatment	Knee muscle exercises	Normal treatment, single guidance to home exercise

Primary Outcome Measures

Name	Time	Method
Functional tests, pain	baseline , 6 weeks after operation (start of training), after 12 months training	Timed-Up and Go-test, Visual analogue scale (VAS)

Secondary Outcome Measures

Name	Time	Method
Knee muscle strength	baseline, 6 weeks after operation (start of training), after 12 months training	isometric strength of quadriceps and hamstrings
Health related quality of life	baseline and 12 months	SF-36
gait analysis	baseline, 6 weeks postoperatively, 12 months

Trial Locations

Locations (1)

Ceneral Finland Health Care District; 🇫🇮 Jyväskylä, Finland