Effect of ursodeoxycholic acid on breast milk jaundice
Phase 1
- Conditions
- Breast milk jaundice.Neonatal jaundice from breast milk inhibitor
- Registration Number
- IRCT2017013028154N1
- Lead Sponsor
- Vice chancellor for research of Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
birth weights 2500 to 4000 gram; being exclusively breastfed; gestational age of 38 to 41 weeks; age more than 7 days old; total bilirubin level of 14 to 20 mg/dL; direct bilirubin level less than 2 mg/dL. Exclusion criteria: infants with ABO and RH incompatibility; glucose 6-phosphate dehydrogenase deficiency; direct hyperbilirubinemia; septicemia; diseases leading to hyperbilirubinemia (Crigler-Najjar syndrome, gilbert syndrome, hypothyroidism and hyperthyroidism, liver diseases, premature neonates and the infants of diabetic mothers)
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total bilirubin level. Timepoint: Before intervention, 12, 24 and 48 hours after intervention. Method of measurement: mg/dl.
- Secondary Outcome Measures
Name Time Method