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Clinical Trials/NCT03496259
NCT03496259
Terminated
Not Applicable

On-Q Pump vs Epidural for Postoperative Pain Control in Children Undergoing Oncologic Surgery

Baylor College of Medicine1 site in 1 country32 target enrollmentSeptember 1, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Postoperative Pain
Sponsor
Baylor College of Medicine
Enrollment
32
Locations
1
Primary Endpoint
Additional narcotic use
Status
Terminated
Last Updated
4 years ago

Overview

Brief Summary

Open abdominal and pelvic surgery or thoracotomy (open chest surgery) is frequently performed for tumor excision in children. Post-operative pain management regimens are often at the discretions of the attending surgeon and may include opiods, patient administered analgesia (PCA), epidural catheters, subcutaneous analgesia catheters or NSAIDS to control incisional pain. Currently, both epidural or subcutaneous analgesia catheters (On-Q pumps) are commonly used for children undergoing these operations, at the discretion of the surgeon. There are no studies comparing these regimens in children. The purpose of this study is to compare postoperative pain control of the two strategies.

Detailed Description

The study design is a randomized, controlled trial to compare the effectiveness of on-q pump subcutaneous incisional analgesia to epidural analgesia for postoperative pain relief in children undergoing open abdominal, thoracic, or pelvic operations for oncologic purposes. The patient and treating team will be blinded to the pain control device. The primary outcome is additional narcotic usage for 3 post-operative days, and secondary outcomes are pain scores for 3 post-operative days, post-surgical day of ambulation, time to regular diet, infectious complications (UTI, wound infection or pneumonia), and hospital length of stay. Outcomes from both groups will be directly compared in order to determine whether one strategy provides more effective pain control with less complications than the other, or whether they are equivalent.

Registry
clinicaltrials.gov
Start Date
September 1, 2018
End Date
December 1, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Bindi Naik-Mathuria

Associate Professor

Baylor College of Medicine

Eligibility Criteria

Inclusion Criteria

  • Weight \> 5kg
  • Age younger than 19 years of age
  • Planned abdominal, pelvic or thoracic operation for an oncologic indication

Exclusion Criteria

  • Patients deemed inappropriate for placement of epidural by anesthesiologist
  • Minimally invasive operation
  • Biopsy through limited incision
  • History of chronic narcotic or opioid use
  • History of drug abuse

Outcomes

Primary Outcomes

Additional narcotic use

Time Frame: 3 days

Mg of additional narcotics used for 3 post-operative days

Secondary Outcomes

  • Pain scores(3 days)
  • Days to ambulation(0-5 days)
  • Days to initiation of regular diet(0-5 days)
  • Development of postoperative infection(0-5 days)

Study Sites (1)

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