Relationship Between Pressure and Flow Velocity on Coronary Physiology
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Wave intensity
研究概览
简要总结
Subjects are patients who are planned to do percutaneous coronary intervention for coronary stenosis in the left circumflex artery without other stenosis in the left ascending artery and the right coronary artery, or a patient with normal coronary artery. Immediately after coronary angiography or percutaneous coronary intervention, the investigators will evaluate for coronary hemodynamics by distribution of wave intensity which is calcurated by coronary pressure and flow velocity with Combowire in each coronary segment. Also, they will assess coronary morphology by View It in each coronary segment.
详细描述
Combowire (Volcano Therapeutics Inc., CA, USA) is a 0.014 inch pressure/Doppler sensor-tipped-guidewire which can measure coronary pressure and flow velocity.
View It (Terumo Co., Japan) is a guide catheter with intravascular ultrasound which can measure coronary morphology such as vessel diamter.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •A patient who are planned to do percutaneous coronary intervention for stenosis in the left circumflex artery without any lesions in other coronary arteries
- •Or a patient who is performed coronary angiography without significant stenosis lesion in 3-coronary vessel
排除标准
- •A patient with coronary stenosis with LAD
- •Hemodialysis
- •Acute coronary syndrome
- •Congestive heart failure
- •A patient with shock vitals
研究组 & 干预措施
Normal coronary artery
干预措施: combowire and IVUS (Device)
结局指标
主要结局
Wave intensity
时间窗: Immediately after coronary angiography or percutaneous coronary intervention
次要结局
- Vessel diameter(Immediately after coronary angiography or percutaneous coronary intervention)
- Coronary pressure(Immediately after coronary angiography or percutaneous coronary intervention)
- Flow velocity(Immediately after coronary angiography or percutaneous coronary intervention)
研究者
Kenichi Fujii
Relationship between pressure and flow velocity on coronary physiology
Hyogo Medical University