Sleep Apnea in Acromegaly After Surgery

• Conditions: Sleep Apnea

• Registration Number: NCT03526016
• Lead Sponsor: Seoul National University Hospital

Brief Summary

Sleep apnea is common in acromegaly and both diseases are independently associated with hypertension and insulin resistance contributing to increased morbidity and mortality. Respiratory polygraphy is a simpler alternative to in-laboratory polysomnography for the management of more symptomatic patients with obstructive sleep apnea.

The aim of this study is to evaluate the prevalence of sleep apnea by respiratory polygraphy, and to analyze the effect of transsphenoidal surgery on sleep apnea.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-02-21
• Study First Submitted: 2018-05-02
• Study First Submitted QC: 2018-05-15
• Study First Posted: 2018-05-16
• Status Verified: 2021-08
• Last Update Submitted: 2021-08-18
• Last Update Posted: 2021-08-20
• Primary Completion: 2021-12
• Study Completion: 2021-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• patients with newly diagnosed acromegaly

Exclusion Criteria

• patients who can not undergo transsphenoidal surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in Respiratory disturbance index	Baseline and 3 months after transsphenoidal surgery	Changes in respiratory events during sleep

Trial Locations

Locations (1)

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of