NCT03526016UnknownNot Applicable
Effect of Transsphenoidal Surgery on Sleep Apnea in Patients With Acromegaly
Seoul National University Hospital1 site in 1 country50 target enrollmentStarted: February 21, 2018Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Change in Respiratory disturbance index
Study Overview
Brief Summary
Sleep apnea is common in acromegaly and both diseases are independently associated with hypertension and insulin resistance contributing to increased morbidity and mortality. Respiratory polygraphy is a simpler alternative to in-laboratory polysomnography for the management of more symptomatic patients with obstructive sleep apnea.
The aim of this study is to evaluate the prevalence of sleep apnea by respiratory polygraphy, and to analyze the effect of transsphenoidal surgery on sleep apnea.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 99 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •patients with newly diagnosed acromegaly
Exclusion Criteria
- •patients who can not undergo transsphenoidal surgery
Outcomes
Primary Outcomes
Change in Respiratory disturbance index
Time Frame: Baseline and 3 months after transsphenoidal surgery
Changes in respiratory events during sleep
Secondary Outcomes
No secondary outcomes reported
Investigators
Jinwoo Lee
Associate professor
Seoul National University Hospital
Study Sites (1)
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