Postural Stability, Balance and Fall Risk in Patients With Obstructive Sleep Apnea

Completed

• Conditions: Obstructive Sleep Apnea

• Registration Number: NCT03589417
• Lead Sponsor: Bezmialem Vakif University

Brief Summary

Obstructive sleep apnea (OSA) is a clinical condition characterized by the repetitive obstruction of the upper airway during sleep, resulting in nocturnal hypoxaemia and fragmented sleep. Fragmented sleep leads to daytime sleepiness that causes alterations in reaction times and reflexes . Postural stability is an important function of the human body. It is shown that the sleep deprivation disturbs daytime postural stability and balance. Aim of this study is to examine the influence of OSA severity and daytime sleepiness on postural stability, balance and fall risk.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-07-05
• Study First Submitted QC: 2018-07-05
• Study First Posted: 2018-07-17
• Study Start: 2018-09-24
• Primary Completion: 2019-04-08
• Study Completion: 2019-04-08
• Status Verified: 2019-06
• Last Update Submitted: 2019-06-17
• Last Update Posted: 2019-06-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Subjects with recent diagnosis of OSA (AHI≥5)
• BMI of ≤35 kg/m2
• Being sedentary

Exclusion Criteria

• Having OSA treatments (CPAP, oral devices, nasal surgery, tennis ball/positional therapy, diuretic),
• Having a disease that can affect balance (vestibular, neurological, orthopedic ...) performing regular exercise
• Morphological defect (facial malformation, etc.) which may cause sleep disorders
• Uncontrolled hypertension or arrhythmia
• History of smoking or alcoholism
• Orthopedic, neurological or musculoskeletal problems which impede exercising
• Pregnancy
• Uncompensated clinical conditions such as chronic obstructive pulmonary disease, interstitial lung disease, heart failure, or rheumatic and psychiatric diseases

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Limits of Stability Test score	Baseline	'Limits of Stability Test' will be applied with Biodex Balance System®. Subjects will stand on the platform and lean in eight directions to control the cursor displayed on the screen and try to move the cursor inside the target circles. Test provides scores for all eight directions as well as an overall score. Higher scores indicate better performance (0= worst performance; 100= perfect performance)
Fall risk Test score	Baseline	'Fall Risk Test' will be applied with Biodex Balance System®. Subjects will stand still on the platform which will gradually become more unstable for 20 seconds. Total displacement of the centre of gravity will be quantified. Test provides one score: Overall stability index. Higher score indicates higher risk of fall.
Postural Stability Test score	Baseline	'Postural Stability Test' will be applied with Biodex Balance System®. Subjects will stand still on the platform and the displacement of the centre of gravity will be quantified for anterior-posterior (AP) and medial-lateral (ML) axes. Test provides three types of scores: overall stability index, anterior-posterior stability index and medial-lateral stability index. Higher scores indicate worse postural stability.

Trial Locations

Locations (1)

Bezmialem Vakif Universitesi, Department of Physiotherapy and Rehabilitation; 🇹🇷 Istanbul, Eyup, Turkey