inking Substrate Based Electrogram Characteristics with Activation Patterns to Develop Individualized Ablation Strategies for Atrial Fibrillatio

Phase 4

• Conditions: I48.0; I48.1; Paroxysmal atrial fibrillation; Persistent atrial fibrillation

• Registration Number: DRKS00011808
• Lead Sponsor: Städtisches Klinikum KarlsruheMedizinische Klinik IV

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-04-01
• Study Completion: 2021-04-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

Clinical indication for catheter ablation due to atrial fibrillation or atrial flutter.

Exclusion Criteria

- Left atrium > 55mm
- Left atrial thrombus
- Instable Angina pectoris / present myokardial infarction < 3 month
- Mitral regurgiation
- NYHA III-IV
- Stroke/TIA < 3 month
- uncontrolled hyperthyreodism
- Pregnancy
- Life expectancy < 1 year
- Contraindication for oral anticoagulation
- Mitral prothesis

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Compilation of the maps and analysis of a local overlap between the different mapping techniques: CFAEs, rotors, low-voltage

Secondary Outcome Measures

Name	Time	Method
Determination of the excitation patterns in the retrospective analysis of the data. Division into substrate-based, functional, active and passive.