Post operative analgesic efficacy of dexmedetomidine with bupivacaine in wound infiltration for lower abdominal surgries
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- duration and efficiency of post operative analgesia after wound infiltration
研究概览
简要总结
This is a prospective randomized study for post operative analgesic efficacy of wound infiltration of bupivacaine alone and with combinations of two comparative doses of dexmedetomidine.
The post operative analgesia upto 48hours post operative period is observed and also the time for first rescue analgesia ( inj tramadol in our study) is observed.
75 study patients divided randomly into 3 groups (25 in each group)
GroupB = Inj.Bupivacaine Hydrochloride 0.25% 18 ml + Placebo (Normal Saline 0.9%) 2 ml 0.9%NS
GroupBD(I)= Inj. Bupivacaine Hydrochloride 0.25% 18 ml + Inj.Dexmetedomine 0.5 mcg/kg 2 ml 0.9% NS
GroupBD(II)= Inj. Bupivacaine Hydrochloride 0.25% 18 ml + Inj.Dexmetedomine 1 mcg/kg 2 ml 0.9% NS
Ø Thehypothesis of our study is that dexmedetomedine when added as an adjuvant tobupivacaine in wound infiltration in lower abdominal surgries, potentiatesaction of bupivacaine and duration of post operative pain relief will be longeras compared to bupivacaine alone.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA I & II SCHEDULED FOR LOWER ABDOMINAL SURGERIES.
排除标准
- •Patient refusal Patients with H/o cardiac, respiratory, renal or hepatic dysfunction or failure Coagulation disorders Psychological disorders Allergy to study medications Chronic use of pain medications Adrenoreceptors agonists or antagonists Patients with H/o Motion sickness Patient with Body mass index > 35 Women who are in menstruation.
结局指标
主要结局
duration and efficiency of post operative analgesia after wound infiltration
时间窗: duration of post operative analgesia 48 hour after wound infiltration
次要结局
- The effectiveness and onset of post operative analgesia,sedation and complications if any.(48 hour post operative period)