MedPath

GEM study for ectopic pregnancy

Phase 1
Conditions
Ectopic pregnancy or pregnancy of unknown location.
MedDRA version: 14.0 Level: PT Classification code 10014166 Term: Ectopic pregnancy System Organ Class: 10036585 - Pregnancy, puerperium and perinatal conditions
Therapeutic area: Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13]
Registration Number
EUCTR2011-001747-69-GB
Lead Sponsor
Monash University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
Not specified
Target Recruitment
30
Inclusion Criteria

1. Women aged between 18 and 45 inclusive
2. Women with serum hCG greater than 5
3. Women with either a mass which on ultrasound has the appearance of an ectopic pregnancy or a pregnancy of unknown location
4. No clinical evidence of intra-uterine bleeding
5. No pallor
6. No guarding/rigidity on abdominal examination
7. Stable blood pressure and heart rate
8. Normal haemaglobin on full blood examination at day 1.
Are the trial subjects under 18? no
Number of subjects for this age range: 0
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 50
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range 0

Exclusion Criteria

1. History of significant pulmonary disease (eg lung carcinoma including mesothelioma, chronic obstructive airways disease, emphysema, pneumonitis, silicosis, pulmonary fibrosis, severe/brittle asthma, ILD)
2. Abnormal liver indices
3. Abnormal renal indices
4. Abnormal haematological indices
5. Significant pre-existing dermatological condition (eg psoriasis, excema)
5. Significant pre-existing gastrointestinal illness (eg inflammatory bowel disease, bowel carcinoma)
6. Japanese ethnicity.

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath