Comparison of drugs used for prolonging pain control under spinal anaesthesia
- Conditions
- Medical and Surgical,
- Registration Number
- CTRI/2022/05/042755
- Lead Sponsor
- SMS Hospital
- Brief Summary
Many adjuvants are used to increase the duration of postoperative analgesia , however little literature is available for adjuvants like buprenorphie and Midazolam . We hypothesize that these agents when added to intrathecal Bupivacaine 0.5% would prolong the duration of postoperative analgesia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 90
- 1Patients of either sex 2Age group between 25 and 55 years 3ASA grade I & II 4Body weight 45 to 65 kg 5Undergoing lower abdominal surgeries like Ovarian cystectomy, herniorraphy, abdominal hysterectomy.
- (Duration 60-90 min).
1 Patients not willing to participate in the study 2Cases with sepsis, bacteremia or skin infection of local site 3History of severe hypovolemia, anemia and compromised renal, cardiac or respiratory status 4Cases with raised intracranial tension 5History of blood coagulopathies 6Patient allergic to drugs used for study 7Uncooperative patients 8Failure of spinal anesthesia, cases in which general anaesthesia will be required.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean time duration for the need of first rescue analgesia At end of surgery then post-op 30 min ,60min 90min,120min,150min,180min,210min 4hr,6hr,8hr,12hr,24hr
- Secondary Outcome Measures
Name Time Method •To assess and compare the onset time and duration of Sensory and Motor block. •To assess and compare Hemodynamic parameters: (Heart Rate; Mean Blood Pressure; Systolic Blood Pressure; Diastolic Blood Pressure), Sedation score and VAS score.
Trial Locations
- Locations (1)
SMS Hospital
🇮🇳Jaipur, RAJASTHAN, India
SMS Hospital🇮🇳Jaipur, RAJASTHAN, Indiadr samridhi nandaPrincipal investigator9680565399samridhinanda@gmail.com