Adult HMO Supplementation and the Gut Microbiome
- Conditions
- Healthy Adults
- Registration Number
- NCT06570330
- Lead Sponsor
- Seeding, Inc DBA Tiny Health
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not yet recruiting
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria:<br><br> - Participants are between the ages of 18 and 40.<br><br>Exclusion Criteria:<br><br> - Participants cannot have taken prebiotic or probiotic supplements within 6 months of<br> starting study. This includes prebiotic or probiotic powder or supplements with<br> prebiotic or probiotic addition or multivitamin with probiotic addition. This does<br> not include food with live probiotics in it like yogurt or kefir.<br><br> - Participants must not be pregnant or breastfeeding or trying to conceive within<br> the study period.<br><br> - Participants must be residents of the United States with US postal service.<br><br> - Participants cannot have the following existing health conditions:<br><br> - Pre-existing gut conditions (IBD, Celiac's disease, Crohn's disease, SIBO)<br><br> - Immune or auto-immune conditions (Type 1 Diabetes, human immunodeficiency<br> virus (HIV))<br><br> - Participants cannot be lactose intolerant or have an allergy to dairy products.<br><br> - Participants are excluded if they have received results from an at home<br> microbiome stool test in the past 6 months. This does not include clinical<br> workup such as culture or pathogen testing.<br><br> - Participants must agree not to take another prebiotic or probiotic supplement<br> or an at-home test over the study period.<br><br> - Participants must have no known major dietary changes upcoming.
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quantitative changes in the relative abundance of key bacterial taxa;Detection of presence of specific HMO digestion genes;Assess Changes in the diversity metrics of the Gut Microbiome;Evaluate Changes in Metabolic Markers;Evaluate Changes in Inflammation Markers
- Secondary Outcome Measures
Name Time Method