Concurrent Training and Prediabetes Control

Not Applicable

Completed

• Conditions: Metabolic Disturbance
• Interventions: Behavioral: Endurance training plus resistant training

• Registration Number: NCT03502304
• Lead Sponsor: Universidad Santo Tomas

Brief Summary

Despite exercise training decrease blood fasting glicaemy in 'average' terms, there is a wide inter-individual variability after exercise training explored mainly in adults but not in adults with prediabetes comorbidities. Thus, is yet unknown the effects and influence of the concurrent training (CT) eliciting responders (R) and non-responders (NR) cases (i.e., percentage of subjects who experienced a non-change/worsened response after training in some metabolic outcomes).

Detailed Description

Not available

Study Timeline

• Study Start: 2017-06-10
• Primary Completion: 2018-04-09
• Study Completion: 2018-04-09
• Study First Submitted: 2018-04-09
• Study First Submitted QC: 2018-04-17
• Study First Posted: 2018-04-18
• Status Verified: 2018-05
• Last Update Submitted: 2018-05-29
• Last Update Posted: 2018-05-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 28

Inclusion Criteria

• Written informed consent.
• Interested in improving health and fitness.

Exclusion Criteria

• Cardiovascular contraindications to exercise,
• History of stroke, asthma or chronic obstructive pulmonary disease,
• Muscle-skeletal disorders, and
• Smoking.
• A compliance rate to the exercise program ≥ 70% was required for the participants in the intervention group to be included in the statistical analyses.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Endurance training plus resistant training	Endurance training plus resistant training	To concurrent training (endurance training plus resistant training, RT) program will be use cycle ergometers adapted for obese adults (OXFORDTM, model BE2601, OXOFORD Inc, Santiago, Chile) were used. Prior to the CT intervention, all subjects were familiarized (during 3 sessions) with the training protocols. The CT intervention included 3 weekly sessions of both ET and RT. The core part of each session included RT followed by ET exercises (for 50 and 30 minutes, respectively) and was preceded and followed by a 5-minute warm-up and cool-down with callisthenic movements.
Control group	Endurance training plus resistant training	No-exercise

Primary Outcome Measures

Name	Time	Method
Fasting glucose	Baseline and 20-weeks immediately after the interventions ends	Change from Baseline in fasting glucose
Lipoproteins	Baseline and 20-weeks immediately after the interventions ends	Change from baseline in lipoproteins

Secondary Outcome Measures

Name	Time	Method
Body mass	Baseline and 20-weeks immediately after the interventions ends	Change from Baseline in body mass
Waist circumference	Baseline and 20-weeks immediately after the interventions ends	Change from Baseline in waist circumference
Fat mass	Baseline and 20-weeks immediately after the interventions ends	Change from Baseline in fat mass
Lean mass	Baseline and 20-weeks immediately after the interventions ends	Change from Baseline in lean mass
Heart rate at rest	Baseline and 20-weeks immediately after the interventions ends	Change from Baseline in heart rate at rest
Six minutes walking test	Baseline and 20-weeks immediately after the interventions ends	Change from Baseline in six minutes walking test

Trial Locations

Locations (1)

Cristian Alvarez; 🇨🇱 Los Lagos, Osorno, Chile