Concurrent Training and Prediabetes Comorbidities: An Analysis of Non-responders Using Clinical Cutoff Points
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Fasting glucose
研究概览
简要总结
Despite exercise training decrease blood fasting glicaemy in 'average' terms, there is a wide inter-individual variability after exercise training explored mainly in adults but not in adults with prediabetes comorbidities. Thus, is yet unknown the effects and influence of the concurrent training (CT) eliciting responders (R) and non-responders (NR) cases (i.e., percentage of subjects who experienced a non-change/worsened response after training in some metabolic outcomes).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 30 Years 至 59 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Written informed consent.
- •Interested in improving health and fitness.
排除标准
- •Cardiovascular contraindications to exercise,
- •History of stroke, asthma or chronic obstructive pulmonary disease,
- •Muscle-skeletal disorders, and
- •A compliance rate to the exercise program ≥ 70% was required for the participants in the intervention group to be included in the statistical analyses.
研究组 & 干预措施
Control group
No-exercise
干预措施: Endurance training plus resistant training (Behavioral)
Endurance training plus resistant training
To concurrent training (endurance training plus resistant training, RT) program will be use cycle ergometers adapted for obese adults (OXFORDTM, model BE2601, OXOFORD Inc, Santiago, Chile) were used. Prior to the CT intervention, all subjects were familiarized (during 3 sessions) with the training protocols. The CT intervention included 3 weekly sessions of both ET and RT. The core part of each session included RT followed by ET exercises (for 50 and 30 minutes, respectively) and was preceded and followed by a 5-minute warm-up and cool-down with callisthenic movements.
干预措施: Endurance training plus resistant training (Behavioral)
结局指标
主要结局
Fasting glucose
时间窗: Baseline and 20-weeks immediately after the interventions ends
Change from Baseline in fasting glucose
Lipoproteins
时间窗: Baseline and 20-weeks immediately after the interventions ends
Change from baseline in lipoproteins
次要结局
- Body mass(Baseline and 20-weeks immediately after the interventions ends)
- Waist circumference(Baseline and 20-weeks immediately after the interventions ends)
- Fat mass(Baseline and 20-weeks immediately after the interventions ends)
- Lean mass(Baseline and 20-weeks immediately after the interventions ends)
- Heart rate at rest(Baseline and 20-weeks immediately after the interventions ends)
- Six minutes walking test(Baseline and 20-weeks immediately after the interventions ends)