Is the Vaginal Microbiome and Metabolome Associated With Spontaneous Preterm Birth (sPTB) in Multiple Pregnancies?

Active, not recruiting

• Conditions: Preterm Birth; Twin Monochorionic Monoamniotic Placenta; Twin; Pregnancy, Affecting Fetus or Newborn; Vaginal Microbiome; Cervical Stiffness; Preterm Labor; Multiple; Pregnancy, Complicated; Twin Dichorionic Diamniotic Placenta

• Registration Number: NCT06053697
• Lead Sponsor: University of Liverpool

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-8-4
• Last Update Posted: 23 September 2024

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: Female
• Target Recruitment: 120

Inclusion Criteria

Inclusion Criteria:<br><br> - Age =18 years<br><br> - Twin pregnancy<br><br> - Able to provide informed consent<br><br>Exclusion Criteria:<br><br> - Known or suspected severe structural/chromosomal fetal abnormality<br><br> - Non-English speaking

Exclusion Criteria

Not provided

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome will be spontaneous preterm birth (sPTB) <34 weeks' gestation.