Etiologies, Investigations and Outcomes of Patients Presenting With Hemoptysis in a North-American Tertiary Center at the Beginning of the 21st Century
试验速览
- 阶段
- 不适用
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Etiologies of hemoptysis
研究概览
简要总结
The study consist of a retrospective analysis of the etiologies, investigations and outcomes of patients presenting between 2005 to 2010 with hemoptysis in a North-American Tertiary center.
详细描述
RATIONALE:
Hemoptysis, mild or massive, is worrisome for both patients and physicians. The management is different depending on the causes, which are not well defined for the North American population. Despite the fact that this symptom is commonly reported in clinic, there are only a few studies published on this subject in the North-American population. Tuberculosis was a frequent cause of hemoptysis described in populations overseas, which seems less prevalent in the investigators center.
Also, there are no known official guidelines regarding the investigation and management of hemoptysis. The investigators hypothesized that the use of modern technology in a North American population may result in different findings and provide a more accurate diagnostic approach.
Therefore, the study compares the different etiologies of hemoptysis and investigation modalities used in patients presenting in a North-American tertiary center.
METHOD:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Any patient over the age of 18 presenting with:
- •A diagnosis of hemoptysis on an outpatient basis.
- •A diagnosis of hemoptysis during consultation in the emergency department.
- •A diagnosis of hemoptysis on the admission sheet.
- •A diagnosis of hemoptysis when hospitalized.
- •A complication of hemoptysis
- •Hemoptysis on the report of the bronchoscopy, chest computed tomography, pulmonary angiography, ventilation-perfusion single-photon emission computed tomography or blood transfusion.
排除标准
- •Patients under 18 years of age.
- •Patient who refused investigation for hemoptysis.
- •Incomplete medical chart
结局指标
主要结局
Etiologies of hemoptysis
时间窗: 5 years
Defining the prevalence of pulmonary diseases by measuring the percentage of patients presenting with hemoptysis caused by lung cancer, bronchiectasis, pulmonary embolism, arteriovenous fistula, pneumonia, bronchitis, tuberculosis, mycosis, heart failure, pseudohemoptysis, cryptogenic and other causes.
次要结局
- All-cause mortality at 2 years(2 years)
- Sensitivity of chest X-ray, chest CT-scan and CT-angiography, bronchoscopy, ventilation-perfusion with single-photon emission computed tomography and pulmonary angiography.(5 years)
- Smoking status(Day 1)
- Age(Day 1)
- Gender(Day 1)
- International Normalized Ratio(Day 1)
- Partial Thromboplastin Time(Day 1)
- Platelet count(Day 1)
研究者
Brian Grondin-Beaudoin
Medical Doctor
Université de Sherbrooke