BeSt Treatment Strategies. A randomized clinical trial to test the effectiveness of different treatment-strategies in patients with early rheumatoid arthritis. Long term follow-up.
Completed
- Conditions
- All patients continue treatment according to the treatment group they were allocated to at the beginning of the BeSt trial. All treatment adjustments will continue to be based on threemonthly DAS measurements, aiming at DAS =<2.4 (or <1.6 before medication may be stopped altogether).
- Registration Number
- NL-OMON22114
- Lead Sponsor
- Schering-PloughCentocor
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 500
Inclusion Criteria
All patients who completed participation in the first 2 years of BeSt.
Exclusion Criteria
N/A
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Functional ability as measured by HAQ;<br /> <br>2. Radiological damage as measured by Sharp/van der Heijde score of hands and feet;<br /><br>3. Side effects and extra-articular manifestations (as reported and as monitored through laboratory assessments, X-rays, DEXAs).
- Secondary Outcome Measures
Name Time Method 1. Quality of life; <br /><br>2. Utilities; <br /><br>3. Work participation; <br /><br>4. Costs.