Effects of Yoga and Conventional Physiotherapy Programs on Fatigue, Balance, Walking and Quality of Life in Multiple Sclerosis Patients.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- MS Walking Scale (MSWS-12)
研究概览
简要总结
Objective
The objective of this study will be to compare the effects of an eight-week Yin-based yoga program and conventional physiotherapy on fatigue, balance, gait, and quality of life in individuals with Multiple Sclerosis (MS).
Methods
Twenty patients with MS will be randomly assigned to either a yoga group (n = 10) or a physiotherapy group (n = 10). Both groups will participate in supervised sessions lasting 60 minutes per day, three days per week, over an eight-week period.
The yoga intervention will be Yin-based, incorporating centering, yoga postures, breathing exercises, and relaxation.
The physiotherapy program will consist of aerobic training, strengthening and spinal stabilization exercises, balance and coordination activities, and stretching.
Outcome measures will include the Fatigue Severity Scale (FSS) for fatigue, the Berg Balance Scale (BBS) for balance, the 12-item Multiple Sclerosis Walking Scale (MSWS-12) for gait, and the Multiple Sclerosis Quality of Life Questionnaire (MSQOL-54) for physical and mental health-related quality of life.
详细描述
Intervention Protocol Yoga Program
The yoga intervention will be implemented in small groups of up to five participants, three times per week for a duration of eight weeks. Sessions will be led by a physiotherapist experienced in working with multiple sclerosis (MS) patients and certified in yoga practice. Each session will last 60 minutes and will consist of four structured components:
Centering/Meditation (5-10 minutes):
Participants will perform breath-focused meditation in a comfortable seated position, using cushions if required. The duration will begin at 5 minutes during the first week and will gradually increase to 8-10 minutes by the third week. Participants will be instructed to count their breaths up to ten, restarting from one if their focus drifts.
Yin and Yang Yoga Poses (40 minutes):
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Being between 18-65 years of age.
- •Voluntarily giving informed consent to participate in the study.
- •Having either Relapsing-Remitting MS (RRMS) or Secondary Progressive MS (SPMS) type.
- •An Expanded Disability Status Scale (EDSS) score of 5.5 or below.
- •No MS exacerbation within the last 4 weeks.
- •Possessing the willingness, ability, and cognitive intactness to participate in the interventions.
排除标准
- •Using medication specifically for fatigue.
- •Presence of major sleep disorders, clinical depression, hypothyroidism, or B12 deficiency.
- •Severe balance problems (e.g., Central Vestibular Disorders (CVO), peripheral neuropathy, Meniere's disease, vertigo).
- •Having received corticosteroid treatment within the last 4 weeks.
- •Pregnancy.
- •Serious cardiovascular disease, hypertension, or orthopedic limitations.
- •Presence of Carpal Tunnel Syndrome.
研究组 & 干预措施
yoga
Participants in the yoga group received a total of 8 weeks of intervention, conducted 3 days a week, for 60 minutes per day. The program components were:
- 8 minutes of meditation practice.
- 40 minutes of Yin and Yang yoga postures. (It's highly recommended to briefly explain what "Yin and Yang yoga postures" specifically entail in the full paper's methodology section, e.g., "Yin yoga focuses on holding passive poses for longer durations to target deep connective tissues, while Yang yoga incorporates more active, flowing sequences to build strength and flexibility.")
- 2 minutes of breathing exercises (pranayama).
- 10 minutes of deep relaxation (savasana).
干预措施: yoga (Other)
Conventional Physiotherapy
Participants in the conventional physiotherapy group also underwent an 8-week program, 3 days a week, for 60 minutes per day. This program included:
- Aerobic exercises.
- Stretching exercises.
- Strengthening exercises.
- Spinal stabilization exercises.
- Balance exercises.
干预措施: conventional physiotheraphy (Other)
结局指标
主要结局
MS Walking Scale (MSWS-12)
时间窗: 3 months
The MSWS-12 is a 12-item self-reported questionnaire that assesses the impact of MS on walking ability over the past two weeks. Items are rated on a 5-point scale (1: almost never, 5: extremely). Higher scores indicate greater perceived walking limitations or difficulties
MS Quality of Life-54 (MSQOL-54)
时间窗: 3 months
The MSQOL-54 is a disease-specific quality of life questionnaire for MS patients. It comprises 31 questions divided into three sub-dimensions: psychological, physical, and psychosocial quality of life. Lower scores indicate a higher quality of life
MS Walking Scale (MSWS-12)
时间窗: 3 months
The MSWS-12 is a 12-item self-reported questionnaire that assesses the impact of MS on walking ability over the past two weeks. Items are rated on a 5-point scale (1: almost never, 5: extremely). Higher scores indicate greater perceived walking limitations or difficulties
MS Quality of Life-54 (MSQOL-54)
时间窗: 3 months
The MSQOL-54 is a disease-specific quality of life questionnaire for MS patients. It comprises 31 questions divided into three sub-dimensions: psychological, physical, and psychosocial quality of life. Lower scores indicate a higher quality of life
次要结局
- Fatigue Severity Scale (FSS)(3 months)
- Berg Balance Scale (BBS)(3 months)
- Fatigue Severity Scale (FSS)(3 months)
- Berg Balance Scale (BBS)(3 months)
研究者
Nursel Oziri
PhD
Istanbul Rumeli University