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Methylphenidate, rivastigmine or haloperidol in hypoactive delirious intensive care patients: a single centre, randomized, mono-blind pilot trial

Completed
Conditions
10012221
ICU-psychosis
Registration Number
NL-OMON31220
Lead Sponsor
niversitair Medisch Centrum Utrecht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
80
Inclusion Criteria

Older than 18 years.
Diagnosed as hypoactive delirium

Exclusion Criteria

Pregnancy; epilepsy; M. Parkinson; Lewy-body dementia; prolonged QT-time; known allergie to the medicinals used; renal replacement therapy; hepatic encephalopathy; hypertheroid; glaucoma; previous suicide attempts; syndrome of Gilles de la Tourette; patients which cannot receive the medication oraly or through a nasogastric tube.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>- the feasibility of a large randomized, placebo controlled, dubbleblind<br /><br>clinical trial to investigate the use of methylfenidate, rivastigmine or<br /><br>haloperidol in hypoactive ICU-delirium.</p><br>
Secondary Outcome Measures
NameTimeMethod
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