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Clinical Trials/NCT05849194
NCT05849194
Completed
Not Applicable

Role of Early Point of Care Ultrasound in Management of Sepsis in Emergency Department

Alexandria University1 site in 1 country200 target enrollmentAugust 1, 2023
ConditionsSepsis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sepsis
Sponsor
Alexandria University
Enrollment
200
Locations
1
Primary Endpoint
Diagnostic accuracy of POCUS approach compared with the definitive diagnosis.
Status
Completed
Last Updated
last year

Overview

Brief Summary

Aim of the study is to determine the diagnostic accuracy of point-of-care ultrasound and to determine its role in sepsis management .

Detailed Description

Two groups of patients will be studied one group will undergo POCUS examination and the other will not undergo POCUS examination then comparison between them will be done regarding accuracy of diagnosis and time taken to reach diagnosis.

Registry
clinicaltrials.gov
Start Date
August 1, 2023
End Date
July 31, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Adult patients admitted to the Emergency Department (ED) of Alexandria Main University Hospital (AMUH) with sepsis.
  • Patients presented with septic shock.

Exclusion Criteria

  • Age less than 18
  • Trauma patients.
  • Pregnant females.
  • Patients with terminal malignancy.
  • Patients taking immunosuppressive drugs or chemotherapy.

Outcomes

Primary Outcomes

Diagnostic accuracy of POCUS approach compared with the definitive diagnosis.

Time Frame: 8 months

The study will include two groups of patients, POCUS group that will undergo point of care ultrasound (POCUS)examination in addition to clinical evaluation and laboratory investigations and control group that will not undergo POCUS examination but only undergo clinical evaluation and laboratory investigations. Both groups will be compared regarding proportion of accurate diagnosis (at emergency department)in relation to the final diagnosis that will be obtained after patient undergo further imaging techniques to search for sepsis such as chest X-ray or CT to look for chest infection and CT abdomen to confirm intra-abdominal sepsis. Unlike trauma, dyspnea and shock up till now there is no validated POCUS protocol to evaluate patients with sepsis.

Secondary Outcomes

  • Time taken to reach diagnosis in both groups(8 months)

Study Sites (1)

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