Pancreatic cancer operation and development of diabetes
Not Applicable
- Conditions
- Health Condition 1: null- All patients with resectable periampullary carcinoma who give informed consent for the study
- Registration Number
- CTRI/2013/12/004233
- Lead Sponsor
- AIIMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 84
Inclusion Criteria
All patients with resectable periampullary carcinoma who give informed consent for the study
Exclusion Criteria
Patients with diabetes mellitus
Patients with pancreatic carcinoma
Patients with periampullary carcinoma with associated pancreatic edema, unclear border or evidence of chronic pancreatitis
ASA grade III / IV
ECOG III / IV
Patients who decline to consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To ascertain the frequency of new-onset diabetes in non-diabetic patients after pancreaticoduodenectomy (PD) <br/ ><br>2.To correlate reduction in volume of pancreatic parenchyma following pancreticoduodenectomy using multi-detector row computed tomography (MDCT) imaging volumetry with development of new onset diabetes.Timepoint: 1.To ascertain the frequency of new-onset diabetes in non-diabetic patients after pancreaticoduodenectomy (PD) <br/ ><br>2.To correlate reduction in volume of pancreatic parenchyma following pancreticoduodenectomy using multi-detector row computed tomography (MDCT) imaging volumetry with development of new onset diabetes.
- Secondary Outcome Measures
Name Time Method 1.To correlate incidence of pancreatic fistula rate with resected pancreatic volume after PD <br/ ><br>2.To find the frequency and correlate reduction in volume of pancreatic parenchyma with onset of exocrine deficiency after PDTimepoint: Patient data will be collected until the time of diagnosis of new onset diabetes or tumuor recurrence or death