NCT05520840已完成不适用
Evaluation of Peripheral Blood Protein Biomarkers for Colorectal Cancer Screening
University Hospital, Rouen3 个研究点 分布在 1 个国家目标入组 350 人开始时间: 2022年12月9日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 350
- 试验地点
- 3
- 主要终点
- Number of patient with advanced neoplasia at colonoscopy
研究概览
简要总结
The aim of the study is to validate the value of value of peripheral blood protein biomarkers in colorectal cancer screening, and to identify new ones
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient aged 50 years or older referred for screening colonoscopy after a positive FIT test or for endoscopic resection of a previously identified suspicious colorectal lesion
排除标准
- •Very high risk of colorectal cancer: Lynch syndrome, Familial adenomatous polyposis, Peutz-Jeghers syndrome, Familial polyposis associated with a MutYH gene defect
- •Other solid cancers or haematological malignancies that are progressive and/or undergoing treatment (apart from basal cell skin carcinoma)
- •Contraindication to total colonoscopy
研究组 & 干预措施
Patient referred for screening colonoscopy or for endoscopic resection
Experimental
Patient aged 50 years or older referred for screening colonoscopy after a positive fecal immunochemical test or for endoscopic resection of a previously identified suspicious colorectal lesion will have a blood sampling for biomarkers detection
干预措施: blood sampling for screening of biomarkers (Diagnostic Test)
结局指标
主要结局
Number of patient with advanced neoplasia at colonoscopy
时间窗: Day 1
Number of patient with presence of best isolated serum biomarkers selected from different candidates
时间窗: Day 1
次要结局
- Number of patient with presence of other isolated serum biomarkers selected from different candidates(Day 1)
研究者
研究点 (3)
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