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临床试验/CTRI/2024/09/073856
CTRI/2024/09/073856尚未招募不适用

Incidence of postoperative pulmonary congestion and acute kidney injury in patients undergoing long duration surgeries and its correlation with intraoperative standard fluid therapy: a prospective observational study.

Dr Anita Sharma1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2024年9月21日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
200
试验地点
1
主要终点
To calculate the incidence of postoperative pulmonary congestion by using lung ultrasound and incidence of postoperative AKI by using renal function tests serum creatinine more than 0.3mg/dl

研究概览

简要总结

This study will be a prospective, single center, observational study to be carried out for a period of one year. Patients of the age group of 18 to 65 years, ASA I and II, undergoing long duration surgery of more than 3 hours will be included in the study. Patients with cardiovascular ailments, morbid obesity, pregnancy, undergoing  cardiothoracic and urologic surgery will be excluded from the study. Lung ultrasound will be performed preoperatively and 1 hour postoperatively by the the same experienced investigator to avoid inter variability. The renal function test will be performed preoperatively and 5 days post operatively. The primary outcome is to calculate  the incidence of postoperative pulmonary congestion and acute kidney injury. The secondary outcome is to see the correlation of total  intravenous fluids, blood and blood products administered intraoperatively with postoperative pulmonary congestion and acute kidney injury.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • The patients of ASA grade I–II who will be undergoing long surgery of duration more than 3 hours.

排除标准

  • Patients with preexisting heart and pulmonary diseases, morbid obesity, pregnancy, surgery duration less than 3 hours, urologic surgery, cardiac surgery.

结局指标

主要结局

To calculate the incidence of postoperative pulmonary congestion by using lung ultrasound and incidence of postoperative AKI by using renal function tests serum creatinine more than 0.3mg/dl

时间窗: Lung ultrasound performed 1 hour after surgery and renal function tests performed 5 days after surgery.

次要结局

  • To correlate the total intravenous fluids, blood and blood products administered intraoperatively with the incidence of pulmonary congestion and acute kidney injury(1 hour after the surgery and 5 days after the surgery)

研究者

发起方
Dr Anita Sharma
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Anita Sharma

Dr Rajendra Prasad Government Medical College Kangra at Tanda

研究点 (1)

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