NCT00484757Unknown不适用
Effect of Intranasal Administration of Orexine A on IL-6-System, Sleep-Wake-Regulation and Neurocognition
Zentrum für Integrative Psychiatrie2 个研究点 分布在 1 个国家开始时间: 2007年6月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 发起方
- 试验地点
- 2
- 主要终点
- Effect of orexine A on sleep, neurocognition and immune-system
研究概览
简要总结
15 patients with narcolepsy and 15 healthy controls will be included in the study. According to a randomized, double-blind protocol they will receive intranasally at night first Orexine A and approximately two weeks later placebo or vice versa. Thereafter sleep will be recorded, the cytokine-system and neurocognition characterized.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Narcolepsy
- •Informed consent
- •GERMAN fluently spoken
排除标准
- •Additional severe psychiatric or somatic disorders
- •Pregnancy or nursing
- •Anemia (Hb<10g/dl)
结局指标
主要结局
Effect of orexine A on sleep, neurocognition and immune-system
次要结局
未报告次要终点
研究者
研究点 (2)
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