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Clinical Trials/NCT06195358
NCT06195358
Recruiting
N/A

Mobile Health Intervention to Promote Positive Infant Health Outcomes in Guatemala

Children's Hospital Los Angeles1 site in 1 country220 target enrollmentJanuary 25, 2024

Overview

Phase
N/A
Intervention
Printed Caregiving Materials
Conditions
Infant Development
Sponsor
Children's Hospital Los Angeles
Enrollment
220
Locations
1
Primary Endpoint
Difference between study arms in Composite Language Score
Status
Recruiting
Last Updated
last month

Overview

Brief Summary

Promoting optimal development for children at risk in low- and middle-income countries (LMICs) is an important global health priority. Supporting caregivers to provide nurturing care is an evidence-based strategy, however feasibility of scaling-up this supporting is limited by competing demands on health workers' time. For infant development, mHealth technologies have the potential to solve this problem by providing tailored content directly to caregivers, involving and empowering them to promote infant development, promoting and facilitating interactions with health workers when areas of concern are identified and, therefore, expanding the reach of healthcare systems. Following a pilot feasibility study, this current study will examine the effectiveness of a caregiver-directed smartphone application to directly engage first-time caregivers in rural Guatemala and support early childhood development.

Detailed Description

Rationale: According to recent estimates, nore than 40% of children under age 5 residing in low- and middle-income countries (LMICs)-250 million children in total-are at risk of not reaching their developmental potential due to living in environments with malnutrition, poverty, and lack of early stimulation. Mobile health (mHealth) technology represents an efficient strategy for scaling interventions to promote infant development. Intervention: Individually-randomized controlled trial of mHealth application compared to paper caregiving materials. Length of intervention = 18 months. Objectives and purpose: We will test the effectiveness of a smartphone application that will directly engage caregivers in providing nurturing care to at-risk infants. We will assess effectiveness of the mHealth application compared to paper caregiving materials by comparing group differences in Bayley scores after 18 months. Study population: first-time parents of newborn infants, newborn infants.

Registry
clinicaltrials.gov
Start Date
January 25, 2024
End Date
July 31, 2026
Last Updated
last month
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Beth Smith

Associate Professor of Pediatrics (USC Faculty/Non Physician CWR)

Children's Hospital Los Angeles

Eligibility Criteria

Inclusion Criteria

  • first-time caregivers with an infant in the eligible age range (0-4 weeks)
  • infant from singleton birth
  • infant from full-term (\> 37 weeks gestation) birth

Exclusion Criteria

  • Presence of acute malnutrition/wasting or severe medical illness (heart disease, kidney disease, congenital abnormality) in the infant
  • medical need for supplementation of breastfeeding
  • caregiver not literate

Arms & Interventions

Control Arm

The control arm will receive printed caregiving materials.

Intervention: Printed Caregiving Materials

Intervention Arm

The intervention arm will receive the smartphone application.

Intervention: Mobile Health (Smartphone) Application

Outcomes

Primary Outcomes

Difference between study arms in Composite Language Score

Time Frame: 18 months

Using the Bayley Scales of Infant Development, 4th Edition (BSID4), higher scores better, scale range 47-153

Difference between study arms in Composite Motor Score

Time Frame: 18 months

Using the Bayley Scales of Infant Development, 4th Edition (BSID4), higher scores better, scale range 46-154

Difference between study arms in Composite Cognitive Score

Time Frame: 18 months

Using the Bayley Scales of Infant Development, 4th Edition (BSID4), higher scores better, scale range 55-145

Secondary Outcomes

  • Change in the Home Observation for Measurement of the Environment Scale (HOME) Raw Score(Change from 0 to 18 months)

Study Sites (1)

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