Inflammation Markers in Hyperemesis Gravidarum
- Conditions
- Hyperemesis Gravidarum
- Registration Number
- NCT06245811
- Lead Sponsor
- Izzet Celegen
- Brief Summary
In this study, the relationship between the severity of hyperemesis gravidarum (HEG) disease and subclinical inflammatory factors such as Platelet Crit (PCT), Hemoglobin/red cell distribution width ratio (HRR), Neutrophil/lymphocyte ratio (NLR), was investigated.
- Detailed Description
A total of 215 pregnant women, 102 with hyperemesis gravidarum and 113 healthy pregnant women, were included in the study. HEG patients were divided into three groups according to the modified PUQE classification: mild (n=38), moderate (n=32) and severe (n=32).
In our study, we proposed using a new prognostic marker for HEG patients. We think that our study will be a source for future studies on HEG.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 215
- Healthy pregnant women over 18 years of age
- 5-16 weeks of gestation.
Smoking, urinary tract infections, previously diagnosed psychological disorders, gastrointestinal disorders, multiple pregnancies, eating disorders, thyroid disorders, inflammatory disease, pregnancy with assisted fertilization technique.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The Pregnancy Unique Quantification of Emesis/Stomach scoring system 2 months 1: Weight loss of 5% or more since the beginning of pregnancy 2: Vomiting at least three times a day 3: A ketonuria value of +1 or higher on a urinalysis test
- Secondary Outcome Measures
Name Time Method Body mass index 2 months (BMI) (kg/m2) was obtained by dividing body weight (kg) by height (m2) squared
Trial Locations
- Locations (1)
Yuzuncu Yil University, Faculty of Medicine
🇹🇷Van, Turkey