Research on Anxiety and Depression: Computer-Assisted Therapy

Not Applicable

Completed

• Conditions: Anxiety Disorders; Mood Disorders
• Interventions: Behavioral: Good Days Ahead

• Registration Number: NCT02817438
• Lead Sponsor: Stanford University

Brief Summary

This study examines how online self-guided programs can improve mood and anxiety symptoms. These programs use exercises from Cognitive-Behavioral Therapy, which is an evidence-based treatment for depression and anxiety. The purpose of this study is to learn who will do best with the online format. Our aim is to learn for whom online self-guided interventions are most efficacious. This knowledge is important because it will help inform clinicians and patients about who might benefit from this type of intervention versus who would need the assistance of a therapist. More specifically, we hope to figure out who would benefit from solely an online intervention and who would benefit from an online intervention in addition to other treatment.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-06
• Study First Submitted: 2016-06-27
• Study First Submitted QC: 2016-06-27
• Study First Posted: 2016-06-29
• Primary Completion: 2018-03
• Study Completion: 2018-03
• Status Verified: 2019-03
• Last Update Submitted: 2019-03-18
• Last Update Posted: 2019-03-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 136

Inclusion Criteria

• Previous participation in the RAD study in our laboratory

RAD study inclusion criteria are:

• 18+ years of age
• Fluent and literate in English
• Can provide informed consent
• fMRI scanning eligibility, including no evidence of any form of metal embedded in the body (e.g., metal wires, nuts, bolts, screws, plates, sutures)

Exclusion Criteria

• Anyone who has not already completed the RAD study will be excluded.

RAD study exclusion criteria are:

• Presence of suicidal ideations representing imminent risk
• General medical condition, disease, or neurological disorder that interferes with the assessments
• Mild traumatic brain injury (history of physical brain injury or blow to the head resulting in loss of consciousness greater than five minutes) and which could interfere with doing the assessments
• Severe impediment to vision, hearing and/or hand movement, likely to interfere with ability to complete the assessments
• Unable and/or unlikely to follow the study protocols
• Pregnant or breastfeeding

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Online Intervention	Good Days Ahead	Participants randomized to the online intervention arm will be given access to the Good Days Ahead program for 12 weeks.

Primary Outcome Measures

Name	Time	Method
Depression and Anxiety Composite Score	12 weeks	Composite score combining 3 measures of depression and/or anxiety (PHQ-9, BAI, DASS)

Secondary Outcome Measures

Name	Time	Method
Quality of Life	12 weeks	WHOQOL scale

Trial Locations

Locations (1)

Stanford University; 🇺🇸 Stanford, California, United States