Effects of oral spray product containing 0.3 % cetylpyridinium chloride (CPC), applied after scaling and mechanical cleaning of tooth surface, on oral bacterial flora in adult volunteers.
Not Applicable
- Conditions
- Healthy adult
- Registration Number
- JPRN-UMIN000041140
- Lead Sponsor
- Sunstar Inc. Shizuoka Innovation Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 48
Inclusion Criteria
Not provided
Exclusion Criteria
Subjects orally taking substances that may affect the oral bacterial flora (e.g. antimicrobials, antibiotics). Subjects routinely using mouthwash, mouth rinse, interdental brush, and dental floss. Subjects routinely cleaning their tongues. Smokers. Subjects receiving a treatment for diabetes mellitus. Subjects planning dentist visits during the study period. Pregnant or lactating women. Subjects with a history of allergic reaction to the study product or its ingredients. Subjects who have multiple caries (at least 5 C2 caries). Subjects with severe periodontitis (e.g. with pus discharge or spontaneous bleeding). Subjects determined by subinvestigators to be ineligible for inclusion in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in oral bacterial flora on the next day of professional oral care (SC, PMTC), after 1 week and 3 weeks from starting the use of CPC spray.
- Secondary Outcome Measures
Name Time Method Changes in total count of oral bacteria on the next day of professional oral care (SC, PMTC), after 1 week and 3 weeks from starting the use of CPC spray; and changes in Tongue Coating Index (TCI) from the first day of the study to 3 weeks after starting the use of CPC spray.