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临床试验/NCT04596306
NCT04596306已完成不适用

Laparoscopic Cholecystectomy for Acute Calculous Cholecystitis in the Elderly: More Complex But Equally Safe and Effective. A Retrospective Study on 879 Patients.

Azienda Ospedaliero, Universitaria Pisana1 个研究点 分布在 1 个国家目标入组 876 人开始时间: 2020年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
876
试验地点
1
主要终点
In-hospital morbidity

研究概览

简要总结

With the progressive aging of the population in industrialized countries, acute calculous cholecystitis (ACC) has been constantly increasing among elderly. Because ACC is the most common complication of biliary gallstone disease and the population will become older, ACC in elderly is expected to increase. In 2017, the incidence of gallstone disease in Italian population is was 18.8% in women and 9.5% in men; the prevalence was 15% and 24% at 70 years and 24% and 35% at 90 years for males and females respectively. Since the increase in age is often associated with an increase in comorbidity, fragility, surgery related complications, morbidity and mortality, the surgical indication for gallstone is still debated and often based on anesthetic risk. In order to avoid surgery for elderly and high-risk patients, alternative treatments to surgery have been developed. The present study aimed to compare two groups of patients with acute calculous cholecystitis undergone laparoscopic cholecystectomy, under and over 70 years old and to assess whether laparoscopy can offer the same safety and efficacy to older people.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • acute calculous cholecystitis

排除标准

  • tumors of the biliary tract

结局指标

主要结局

In-hospital morbidity

时间窗: 30 day

In-hospital mortality

时间窗: 30 day

次要结局

  • conversion to open rate(30-day)
  • length of stay(30-day)
  • major complication rate(30-day)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dario Tartaglia

Ph.D.; M.D., Researcher and Principal Investigator

Azienda Ospedaliero, Universitaria Pisana

研究点 (1)

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