Assessing post surgery pain relief in patients undergoing spine surgeries with ketamine (drug) intravenous infusion during surgery
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2020/07/026692
- Lead Sponsor
- Rajarajeswari Medical college and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
American society of Anesthesiologists (ASA) â? and â?¡ of either sex
Patients undergoing lumbar spine surgeries under general anaesthesia.
Aged between 18 to 65 years
Valid informed/explained consent
Exclusion Criteria
Patient with high risk coronary or vascular disease
Patient with hepatic dysfunction
Patient with history of psychosis
Patient with elevated intracranial pressure or traumatic brain injury
Patient with uncontrolled hypertension
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie ketamine's analgesic effects in postoperative pain management for lumbar discectomy patients?
How does intra-operative subanaesthetic ketamine compare to standard-of-care analgesics in postoperative pain relief for single-level lumbar discectomy?
Are there specific biomarkers that predict response to ketamine-based analgesia in spinal surgery patients with chronic pain conditions?
What are the potential adverse events associated with subanaesthetic ketamine infusion during spinal procedures and their mitigation strategies?
How do ketamine's NMDA receptor antagonism properties influence its efficacy in post-spine surgery pain compared to opioid-sparing approaches?