Xanthohumol in the Prevention of Virus-mediated Upper Respiratory Tract Infections in Humans
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Changes in severity and duration of viral infections
研究概览
简要总结
The aim of the present study is to determine if a regular oral supplementation of xanthohumol attenuate the severity of symptoms and duration of´viral infections.
详细描述
In this placebo-controlled study, blood is taken on the first day of the study, followed by a 90-day intervention with xanthohumol or a placebo, which is taken twice daily. Blood samples will be taken on day 0, day 45 and day 90. Should the study participants develop a respiratory infection during the study, they will be asked to perform a self-test.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI >18 kg/m² or < 28kg/m²
排除标准
- •food intolerances
- •food allergies
- •chronic inflammatory diseases
- •metabolic diseases
- •viral or bacterial infections within the last 3 weeks of inclusion
- •intake of immunosuppressive medication
- •severe acute respiratory syndrome coronavirus type 2-infection in the last 4 months
- •influenza infection in the "current" flu season
研究组 & 干预措施
Placebo
Participants consume twice per day a study drink which contains 0 mg soluble Xanthohumol for 90 days
干预措施: Placebo (Dietary Supplement)
结局指标
主要结局
Changes in severity and duration of viral infections
时间窗: 90 days
Changes in score of Wisconsin Upper Respiratory Symptom Survey
次要结局
- Changes in cognitive skills(90 days)
- Changes in blood lipid levels(90 days)
研究者
Prof. Dr. Ina Bergheim
Prof. Dr. Ina Bergheim
University of Vienna