NL-OMON43020已完成不适用
Activation of the innate immune system in patients with primary hyperaldosteronism - Innate immune activation in hyperaldosteronism
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 64(—)
入选标准
- •Patients with PA (primary hyperaldosteronism):
- •- Diagnosis of PA according to current guideline
- •- Age >=18 yrs
- •- Written informed consent;Patients with essential hypertension:
- •- Exclusion of PA according to current guidelines
- •- Age >=18 yrs
- •- Written informed consent
排除标准
- •- Treatment with MR antagonists within the 4 weeks before participation
- •- Diabetes mellitus
- •- Previous cardiovascular events (stroke, TIA, myocardial infarction)
- •- Heart failure
- •- Auto-inflammatory or auto-immune diseases
- •- Use of immunomodulating drugs
- •- Renal failure (MDRD <45)
- •- BMI >35
- •- Previous vaccination within 3 months prior to study entry.
- •- Current infection or clinically significant infections within 3 months before participation (defined as fever >38.5).
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