NCT01417312已完成不适用
Metabolic Effects of a Green Tea Extract in Multiple Sclerosis Patients
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Fasting and postprandial lipid oxidation in grams per hour, assessed by indirect calorimetry, after 3 months intake of green tea extract versus placebo
研究概览
简要总结
This study aims to investigate metabolic effects of a standardized green tea extract, containing a defined amount of epigallocatechin-3-gallate (EGCG), in multiple sclerosis patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with relapsing-remitting multiple sclerosis
- •stable treatment with glatiramer acetate at least 6 months prior to inclusion
- •Expanded disability status scale < 4.5
- •Normal weight, overweight
排除标准
- •Primary or secondary progressive forms of multiple sclerosis
- •Clinically relevant heart, lung, liver, kidney diseases
- •Habitual caffeine intake over 300 mg per day
- •Habitual consumption of green tea
- •Alcohol or drug abuse
研究组 & 干预措施
Green tea extract
Active Comparator
干预措施: Capsules with 160 mg Teavigo (at least 94% EGCG) (Dietary Supplement)
Placebo
Placebo Comparator
干预措施: Placebo (Dietary Supplement)
结局指标
主要结局
Fasting and postprandial lipid oxidation in grams per hour, assessed by indirect calorimetry, after 3 months intake of green tea extract versus placebo
时间窗: Three months
次要结局
未报告次要终点
研究者
Friedemann Paul
Prof, MD
Charite University, Berlin, Germany
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Effect of green tea consumption on pharmacokinetics and pharmacodynamics of nadolol in healthy volunteersHealthy volunteersJPRN-UMIN000006064Fukushima Medical University12
招募中
3 期
Study effect of consumption of green tea extract tablets for amelioration of iron overload and oxidative stress in transfusion-dependent thalassemia patientsThalassemia patientsThalassemia, antioxidantTCTR20211118002The Thailand Research Fund42
已完成
不适用
Evaluation of the effect of green tea extract on the postoperative pain following surgical removal of the impacted mandibular wisdom toothevaluation of the postoperative pain following application of the green tea-impregnated gauze after surgical extraction of the impacted mandibular third molar.Other acute postprocedural painG89.18IRCT20131205015665N4Esfahan University of Medical Sciences32
已完成
不适用
Green Tea Supplementation, Fat Oxidation and Body Composition in Overweight IndividualsOverweight and ObesityFat BurnNCT04628624Anglia Ruskin University30
已完成
不适用
The effects of green tea-derived components on acute upper respiratory tract inflammation for health care workers; single-blinded randomized parallel-group trialAcute upper respiratory tract inflammationJPRN-UMIN000030103niversity of Shizuoka300