Effectiveness of Aspirin in Compare With Heparin Plus Aspirin in Recurrent Pregnancy Loss Treatment

Completed

• Conditions: Recurrent Pregnancy Loss

• Registration Number: NCT01542411
• Lead Sponsor: Yazd Medical University

Brief Summary

This study evaluated the effect of anticoagulant treatment on the live-birth rate in women with a history of at least two continuous unexplained miscarriages or thrombophilia. It also compared two methods of treatment with aspirin and aspirin plus heparin.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-04
• Status Verified: 2012-02
• Study First Submitted: 2012-02-25
• Study First Submitted QC: 2012-03-01
• Last Update Submitted: 2012-03-01
• Study First Posted: 2012-03-02
• Last Update Posted: 2012-03-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 520

Inclusion Criteria

• unexplained recurrent miscarriage,
• women had previous venous or arterial thromboembolism or who were heterozygous or homozygous for mutations for FV Leiden G1691A, prothrombin gene G20210A (FII G20210A), and methyltetrahydrofolate reductase C677T (MTHFR C677T)

Exclusion Criteria

• abnormal karyotypes of both partners,
• uterine and cervical anatomical disorders on pelvic ultrasonography or hysteroscopy,
• abnormal ovaries and abnormal endocrine tests.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Research and Clinical Centre for Infertility; 🇮🇷 Yazd, Iran, Islamic Republic of