Effects of tDCS in M1 and DLPFC on Pain Processing in Healthy Volunteers
Not Applicable
Completed
- Conditions
- Pain Processing in Healthy Volunteers
- Registration Number
- NCT04432363
- Lead Sponsor
- Universidad Rey Juan Carlos
- Brief Summary
The purpose of this study is to evaluate the effects of a direct current applied transcranial over two cortical areas on healthy volunteers' pain processing.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- Age between 18 and 40 years
- Comprehension of the study tasks
Exclusion Criteria
- Presence of pain in the previous 6 months
- Altered sensitivity in the tested regions
- Intolerance to electrotherapy
- Presence of pacemakers or any other implanted device
- Ulcers or scars in the skin at the location of the electrodes
- Treatment with direct current stimulation within one week
- Pregnancy
- Frequent headaches
- Epilepsy
- History of neuromuscular disease
- Previous clinical history of cervical surgery
- Injuries or surgery affecting the upper limb
- diabetes mellitus
- Cardiovascular diseases
- Oncological diseases
- Consumption of analgesic drugs 7 days before the study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Pain pressure algometer temporal summation Pre-intervention and immediately after treatment Change in pain perceived between the first and tenth painful pressure stimulus
Conditioned Pain Modulation Pre-intervention and immediately after treatment Pain pressure threshold change after a painful ischemic stimulus
- Secondary Outcome Measures
Name Time Method Neural mechanosensitivity Pre-intervention and immediately after treatment Measurement of range of motion achieved until the perception of tension
Pain pressure threshold Pre-intervention and immediately after treatment Measurement of pressure applied until the perception of pain
Pain pressure tolerance Pre-intervention and immediately after treatment Measurement of maximal painful pressure tolerate using a pressure algometer
Cold hyperalgesia with a cold pack Pre-intervention and immediately after treatment Pain rated in a visual analogue scale after 10 seconds of a cold stimulus
Isometric grip strength Pre-intervention and immediately after treatment Maximal pressure achieved in a isometric gripping task
Trial Locations
- Locations (1)
Universidad Rey Juan Carlos
🇪🇸Alcorcon, Madrid, Spain
Universidad Rey Juan Carlos🇪🇸Alcorcon, Madrid, Spain