Risk Factor of Postoperative Delirium and Postoperative Cognitive Decline After Cardiac Surgery
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 360
- 试验地点
- 1
- 主要终点
- Postoperative delirium
研究概览
简要总结
Postoperative delirium (POD) and postoperative cognitive decline (POCD) are common after surgeries in the elderly, especially after cardiothoracic surgery. These conditions are associated with adverse short- and long-term outcomes.
Multiple conditions in the perioperative period have been proposed as risk factors of POD and POCD.
Incidences vary across institutions due to differences in screening and diagnostic tools.
详细描述
This is a prospective observational study to identify the incidences and risk factors of postoperative delirium and postoperative cognitive decline after elderly patients undergoing cardiac surgical procedures which require cardiopulmonary bypass and postoperative intensive care unit (ICU) admission.
Patients will be screen for POD and POCD with various psychological tests in the postoperative period and after hospital discharge.
Perioperative data and outcomes will be used to identify risk factors of both conditions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age 65 years old or older
- •undergoing open heart surgery (cardiopulmonary bypass assisted cardiothoracic surgery
排除标准
- •unable to communicate
- •severe visual or hearing impairment
结局指标
主要结局
Postoperative delirium
时间窗: Postoperative day 1-5 (5 consecutive days)
A result consistent with postoperative delirium by using Confusion Assessment Method-ICU (CAM-ICU) in the postoperative period
次要结局
- Postoperative cognitive dysfunction - postoperative(Postoperative day 5-9 (5 consecutive days))
- Postoperative cognitive dysfunction - 3 month(At 3rd month after hospital discharge)
- Postoperative cognitive dysfunction - 1 year(At 12th month after hospital discharge)