Risk Factor of Postoperative Delirium and Postoperative Cognitive Decline After Cardiac Surgery
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Postoperative Delirium
- Sponsor
- Mahidol University
- Enrollment
- 360
- Locations
- 1
- Primary Endpoint
- Postoperative delirium
- Status
- Active, Not Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Postoperative delirium (POD) and postoperative cognitive decline (POCD) are common after surgeries in the elderly, especially after cardiothoracic surgery. These conditions are associated with adverse short- and long-term outcomes.
Multiple conditions in the perioperative period have been proposed as risk factors of POD and POCD.
Incidences vary across institutions due to differences in screening and diagnostic tools.
Detailed Description
This is a prospective observational study to identify the incidences and risk factors of postoperative delirium and postoperative cognitive decline after elderly patients undergoing cardiac surgical procedures which require cardiopulmonary bypass and postoperative intensive care unit (ICU) admission. Patients will be screen for POD and POCD with various psychological tests in the postoperative period and after hospital discharge. Perioperative data and outcomes will be used to identify risk factors of both conditions.
Investigators
Eligibility Criteria
Inclusion Criteria
- •age 65 years old or older
- •undergoing open heart surgery (cardiopulmonary bypass assisted cardiothoracic surgery
Exclusion Criteria
- •unable to communicate
- •severe visual or hearing impairment
Outcomes
Primary Outcomes
Postoperative delirium
Time Frame: Postoperative day 1-5 (5 consecutive days)
A result consistent with postoperative delirium by using Confusion Assessment Method-ICU (CAM-ICU) in the postoperative period
Secondary Outcomes
- Postoperative cognitive dysfunction - postoperative(Postoperative day 5-9 (5 consecutive days))
- Postoperative cognitive dysfunction - 3 month(At 3rd month after hospital discharge)
- Postoperative cognitive dysfunction - 1 year(At 12th month after hospital discharge)