Preoperative Scoring System to Predict the Risk of Lymph Node Metastasis in Cervical Cancer
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 426
- 主要终点
- Overall survival
研究概览
简要总结
The lymph node status is difficult to be assessed preoperatively, this study aimed to develop a scoring system for predicting the risk of LNM in cervical cancer patients before operation.
详细描述
Lymph nodes metastasis (LNM) was proved to be a critical risk factor related to the survival to cervical cancer survival. However, preoperative pelvic magnetic resonance imaging (MR) or computed tomography (CT) tests are less sensitive to assess the risk of lymph node metastasis. PET-CT is too expensive and radiative to be widely used in clinical practice. A model was constructed based on clinical indicators to predict lymph node metastasis preoperatively, providing a reference for clinical treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 25 Years 至 70 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of cervical cancer
- •FIGO stage IB1-IIA1
- •Undergone radical hysterectomy with pelvic lymphadenectomy
- •Peformed pelvic MRI examination preoperatively
排除标准
- •Had distant metastases diagnosed before or during the surgery
- •Underwent neoadjuvant radiotherapy preoperatively
- •Underwent neoadjuvant chemotherapy preoperatively
- •Incomplete or inaccuratemedical records
结局指标
主要结局
Overall survival
时间窗: 60 months
death or loss of follow-up
次要结局
- The accuracy of the model(60 months)
- Risk factors influenced LNM(60 months)
研究者
Yebin Feng
Director
Fujian Maternity and Child Health Hospital