Preoperative Scoring System to Predict the Risk of Lymph Node Metastasis in Cervical Cancer
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cervical Cancer
- Sponsor
- Fujian Maternity and Child Health Hospital
- Enrollment
- 426
- Primary Endpoint
- Overall survival
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
The lymph node status is difficult to be assessed preoperatively, this study aimed to develop a scoring system for predicting the risk of LNM in cervical cancer patients before operation.
Detailed Description
Lymph nodes metastasis (LNM) was proved to be a critical risk factor related to the survival to cervical cancer survival. However, preoperative pelvic magnetic resonance imaging (MR) or computed tomography (CT) tests are less sensitive to assess the risk of lymph node metastasis. PET-CT is too expensive and radiative to be widely used in clinical practice. A model was constructed based on clinical indicators to predict lymph node metastasis preoperatively, providing a reference for clinical treatment.
Investigators
Yebin Feng
Director
Fujian Maternity and Child Health Hospital
Eligibility Criteria
Inclusion Criteria
- •Clinical diagnosis of cervical cancer
- •FIGO stage IB1-IIA1
- •Undergone radical hysterectomy with pelvic lymphadenectomy
- •Peformed pelvic MRI examination preoperatively
Exclusion Criteria
- •Had distant metastases diagnosed before or during the surgery
- •Underwent neoadjuvant radiotherapy preoperatively
- •Underwent neoadjuvant chemotherapy preoperatively
- •Incomplete or inaccuratemedical records
Outcomes
Primary Outcomes
Overall survival
Time Frame: 60 months
death or loss of follow-up
Secondary Outcomes
- The accuracy of the model(60 months)
- Risk factors influenced LNM(60 months)