Modeling Stress-precipitated Vaping Behavior Among E-Cigarette Users
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 51
- 试验地点
- 1
- 主要终点
- latency to initiate ad-lib vaping session (in minutes)
研究概览
简要总结
The primary aims of this pilot study were to (1) initially validate the applicability of a human laboratory model of relapse initially developed for smokers to e-cigarette users; (2) to use this human laboratory model of lapse behavior to examine the effects of acute psychological stress on vaping-lapse behavior among adults who are experienced, e-cigarette users.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •at least 18 years old
- •e-cigarette users
- •using ≥1 mL of e-cigarette liquid per day with a nicotine concentration of ≥3mg/ml
- •had used an e-cigarette for at least three months
排除标准
- •Current smokers
- •Psychiatric or medical condition based
- •Using a prescription medication other than birth control
研究组 & 干预措施
Control task-
The Control Task was implemented to ensure the specificity of the psychological stress effects had on study outcomes. Therefore, the Control Task had a similar procedure and the same duration of the TSST, lacking except for only the psychologically stressful component. The control task consisted of (a) Participants had a 5-min a preparation section and anticipation phase (5 min ), (b) a reading task where they had to. Then, all participants had to be read a simple text in a low voice (5 min), and (c) an arithmetic section where they were asked to perform an easy mathematical calculation (5 mins).
干预措施: Control task and Trier Social Stress Task (Other)
Experimental Task- Trier Social Stress Task
The Trier Social Stress Task (TSST) is a standardized, 15-minute laboratory task designed to induce psychological stress in laboratory settings (Kirschbaum, Pirke, & Hellhammer, 1993). The TSST consists of three continuously successive phases: (a) an anticipation period (5 min); (b) a free speech task (5 min); and (c) a mental arithmetic task (5 min). As is standard in the TSST procedure, participants were told by a research staff member that they would provide a brief speech about "their dream job" in front of a critical audience. At the end of the speech, a member of the audience instructed the participant to conduct serial subtractions as accurately and quickly as possible.
干预措施: Control task and Trier Social Stress Task (Other)
结局指标
主要结局
latency to initiate ad-lib vaping session (in minutes)
时间窗: During the two laboratory sessions which occur within 1 week after screening/baseline.
Time to vaping during the vaping delay task. Range of time delay is 0 minutes to 50 minutes.
number of puffs purchased and consumed during the self-administration period
时间窗: During the two laboratory sessions which occur within 1 week after screening/baseline
Number of e-cigarette uses purchased during the self-administration phase of the vaping delay task. Range of puffs is 0 to 20.
次要结局
- Craving(The VAS will be collected at each laboratory session (within 1 week after screening/baseline) 5 times: baseline (pre task), post task (+15 minutes), decision to smoke (+20 minutes), +30 minutes smoking ab-lib, and +60 minutes during smoking ab-lib)
- Stress(The VAS will be collected at each laboratory session (within 1 week after screening/baseline) 5 times: baseline (pre task), post task (+15 minutes), decision to smoke (+20 minutes), +30 minutes smoking ab-lib, and +60 minutes during smoking ab-lib)
研究者
Irene Pericot-valverde
Research Assistant Professor
Clemson University