Effect of oropharyngeal decontamination by topical antibiotics on the ventilator associated pneumonia

Not Applicable

Recruiting

• Conditions: J95.851; Ventilator associated pneumonia.; Ventilator associated pneumonia

• Registration Number: IRCT20180110038298N1
• Lead Sponsor: Zahedan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 March 2018

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

The age of the patient is between 18 and 65 years
Perform intubation in the first 24 hours and stay at least 72 hours
Clinical pulmonary infection score less than 6 at the time of arrival
Oral hygiene assessment checklist score 10 or less
GCS less than 9

Exclusion Criteria

damage to the mouth, jaw and face
cancer and diabetes and chronic obstructive pulmonary disease
immunosuppression due to certain medications or diseases
history of broad-based antibiotic therapy in the past 3 months
perform a cardiopulmonary resuscitation process

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The incidence of ventilator-dependent pneumonia. Timepoint: At the beginning of the study, before the intervention, and daily until the end of the intervention. Method of measurement: Clinical pulmonary infection score.

Secondary Outcome Measures

Name	Time	Method
Microorganisms grown from pharyngeal and tracheal secretion samples. Timepoint: The first day of the study before the intervention and 5. Method of measurement: Perform culturing in the laboratory by a laboratory collaborator.