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临床试验/NCT01493908
NCT01493908Unknown不适用

The Effect of Price and Marketing Variable on the Pain Controlling Effect of Active Drugs in a Clinical Trial.

Hadassah Medical Organization1 个研究点 分布在 1 个国家目标入组 220 人开始时间: 2012年1月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
入组人数
220
试验地点
1
主要终点
pain thresholds

研究概览

简要总结

The efficacy of the placebo effect has been proved in many prior studies by comparing the symptoms and measures of patients. Placebo has been proved to help in treating illnesses such as depression, stomach ulcer and chronic headaches.

A Meta analysis checked 47 studies about placebo and showed great significance when a patient is treated with placebo pill, no active substance, just by activating conditioning and expectation mechanism in his body, thus providing to the healing process, and that is it's importance.

In recent years studies established a relationship between marketing variables (such as price, label) to the efficacy of a product. In addition- a unique research run in 2008 showed a significant relationship between the marketing strategies and the efficacy of medication; more specifically, patients in this research experienced less (controlled) pain when treated with placebo medication introduced to them as more expensive than patients treated with placebo medication that was introduced to them as much cheaper. All patients were treated with the exact same medication.

In the investigator's experiment the investigators design a laboratory experiment to determine if marketing factors could invoke the placebo effects described earlier. For the initial laboratory experiment, we decided to examine the difference in price, on the efficacy of an OTC analgesic through the mediation of low- voltage electrical pulses to the patient's wrist.

The investigators study hypothesis is that marketing variables such as price and brand name will affect the therapeutic efficacy of an analgesic, i.e. a medicine will have greater influence when the patient is aware of its price compared to one who is not.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy Volunteer participants will be between the ages of 18 and 65

排除标准

  • Candidates who have had a history of cardiac problems, epilepsy, diabetes, or are pregnant will be excluded.
  • Taking no pain medication at the time of the experiment.

研究组 & 干预措施

High price

Active Comparator

干预措施: High price (Drug)

Low price

Active Comparator

干预措施: Low price (Drug)

Low price participants aware paying part

Active Comparator

干预措施: Low price participants aware paying part (Drug)

No price

Active Comparator

干预措施: No price (Drug)

Free of charge

Active Comparator

干预措施: Free of charge (Drug)

结局指标

主要结局

pain thresholds

时间窗: 1hour

Participants will rank their pain thresholds individually and subjectively for a series of pulses. Each participant will experience a series of pulses with random intensity. Pulse intensity will range within 30-90% of the participants maximal level.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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