Phase II study of salvage photodynamic therapy for local failure after definitive chemoradiotherapy for patients with esophageal squamous cell carcinoma
Phase 2
- Conditions
- esophageal squamous cell carcinoma
- Registration Number
- JPRN-C000000244
- Lead Sponsor
- ational Cancer Center Hospital East
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Sex
- All
- Target Recruitment
- 37
Inclusion Criteria
Not provided
Exclusion Criteria
1) No other active malignancy 2) No other severe medical conditions 3) Patients who are suffered systemic infection 4) Patients who cannot keep shading 5) Lesions were judged within mucosal laiyer, and can be treated with EMR 6) Lesions were assessed as T4 before CRT. 7) clinically defined distant or lymph node metastasis by computed tomography and endoscopic ultrasound (EUS) before PDT 8) Patients with porphyria 9) Lesions were not completely evaluated because of stenosis after CRT
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complete response rate of primary site
- Secondary Outcome Measures
Name Time Method Occurence rate of adverse event Progression free survival Overall survival