The TINMAN study
Recruiting
- Conditions
- Postoperative Cognitive Dysfunction (POCD)
- Registration Number
- NL-OMON20874
- Lead Sponsor
- Amsterdam UMC, location AMC - Department of Anesthesiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
In order to be eligible to participate in this study, a patient must meet all of the following criteria:
- Elective minor, moderate or major surgery, according to the definition of the European Society of Anesthesiology
- Age =65 years
- ASA l - lV
- Fluent in written and spoken Dutch
- Willing and able to undergo neuropsychological assessment, and have the MoCA and TICS administered both pre- and approximately one month postoperatively.
Exclusion Criteria
- Emergency surgery
- Previously diagnosed cognitive dysfunction
- Patients who are unable to understand or fill-in questionnaires in Dutch
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method -Agreement between performance on the TICS, MoCA and NPA and its cognitive domains <br> oThe correlation between the TICS, MoCA and total NPA score and baseline characteristics <br> oThe correlation between the TICS, MoCA and the cognitive domain scores of the NPA and baseline characteristics <br> oThe correlation between TICS and MoCA total scores and cognitive domain scores pre- and approximately one month postoperatively
- Secondary Outcome Measures
Name Time Method -The validity, sensitivity and specificity of the TICS and MoCA questionnaires compared to the gold standard (NPA) both on baseline and on postoperative change scores from baseline