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临床试验/CTRI/2024/05/068171
CTRI/2024/05/068171尚未招募不适用

To Determine the Relation Between Respiratory Hospitalization and Aerobic Capacity in Adoloscents With GMFCS Level 1-3 Cerebral Palsy

未提供1 个研究点 分布在 1 个国家目标入组 76 人开始时间: 2024年6月10日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
76
试验地点
1
主要终点
semi standard questionnaire including Number of respiratory related hospitalizations

研究概览

简要总结

Background : 

Cerebral palsy (CP) is a heterogeneous group of permanent movement disorders stemming from non-progressive lesions or abnormalities in the developing brain. Its prevalence is estimated at 2.95 per 1000 children, signifying its significant impact on pediatric health. Respiratory complications have emerged as critical factors contributing to morbidity and mortality among CP individuals, underscoring the urgent need for comprehensive understanding and proactive management of this aspect of the condition.

This study aims to bridge the gap in the literature by investigating the relationship between aerobic capacity and respiratory-related hospitalizations in adolescents with CP. Despite advancements in medical care, respiratory issues persist as formidable challenges for CP individuals. Integrating respiratory function assessments into routine evaluations is imperative to address these challenges effectively and enhance care outcomes.

Methodology:

By employing a methodology, including a semi standard questionnaire for information regarding respiratory associated hospitalization and aerobic capacity testing through shuttle walk/run test, this study endeavors to yield meaningful insights into the correlation between aerobic fitness and respiratory health outcomes in CP adolescents.

Outcome:

The outcome measures encompass GMFCS categorization, BMI assessment using Indian Academy of Pediatrics guidelines, the Physical Activity Readiness Questionnaire for Children - Plus (PARQ-P), and VO2 max calculations. These measures are meticulously chosen to provide comprehensive data for analysis and ensure the reliability and validity of the findings.

Statistical Analysis:

Statistical analysis will be conducted utilizing Spearman’s rank correlation and odds ratios.

In conclusion, this research holds significant promise in advancing our understanding of the complex relationship between aerobic capacity and respiratory health in adolescents with CP. By identifying key associations and risk factors, the study aims to empower healthcare professionals with actionable insights to mitigate respiratory complications, ultimately improving the quality of life and long-term outcomes for individuals living with CP.

研究设计

研究类型
Observational

入排标准

年龄范围
10.00 Year(s) 至 19.00 Year(s)(—)
性别
All

入选标准

  • CEREBRAL PALSY GROUP:
  • Adolescents who are ambulatory and diagnosed with spastic cerebral palsy
  • Age group 10 to 19years
  • GMFCS level I and II
  • GMFCS level III.
  • ambulating and capable of meeting the test criterions.
  • Cognitively, capable of following simple commands
  • Adolescents whose parents / guardians are available with medical records for hospitalization history NORMAL POPULATION:
  • Age matched adolescents.
  • 10 to 19years.

排除标准

  • CEREBRAL PALSY GROUP:
  • GMFCS – level 4 and level 5
  • A severe intellectual disability – Not capable of comprehending with the test instructions.
  • FOR BOTH GROUP:
  • Having undergone surgery in the previous six months.
  • Recent injury
  • Systemic illness that prevents them from performing aerobic testing
  • Respiratory disease or hospitalization –
  • Non-recurrent respiratory episodes (e.g., laryngospasm.
  • Unrelated specific respiratory conditions (e.g., tracheomalacia).

结局指标

主要结局

semi standard questionnaire including Number of respiratory related hospitalizations

时间窗: one time study

次要结局

  • Aerobic capacity ( VO2 max calculation )(one time study)

研究者

发起方
未提供
责任方
Principal Investigator
主要研究者

Shraddha Nayak

The Oxford College Of Physiotherapy

研究点 (1)

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