The Effect of Selenium Supplement on subclinical Hypothyroidism in childre
Phase 3
Recruiting
- Conditions
- Subclinical hypothyroidism.Subclinical iodine-deficiency hypothyroidism
- Registration Number
- IRCT20220314054284N1
- Lead Sponsor
- Gorgan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 148
Inclusion Criteria
Children with subclinical hypothyroidism
Age 3- 16 years
Exclusion Criteria
Dissatisfaction with participating in the study
Failure to follow the patient
Lack of patient medication compliance by parents
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amount of changes in the level of primary variables (TSH). Timepoint: Sections for measuring thyroid hormone levels (TSH) before the intervention and 3 months after (as soon as the treatment period ends). Method of measurement: Comparison of the effect of selenium supplementation on the reduction of TSH level.;The amount of changes in the level of primary variables (selenium). Timepoint: Sections for measuring of selenium level before the intervention and 3 months after (as soon as the treatment period ends). Method of measurement: Comparison of the effect of selenium supplementation on selenium changes.;The amount of changes in the level of primary variables of FT4. Timepoint: Sections for measuring of FT4 level before the intervention and 3 months after (as soon as the treatment period ends). Method of measurement: Comparison of the effect of selenium supplementation on the reduction of T FT4 level.
- Secondary Outcome Measures
Name Time Method Changes in the body's metabolism. Timepoint: Before and 3 months after the start of the intervention. Method of measurement: Evaluation of weight, improvement of patient symptoms including constipation, fatigue, appetite, brittle nails and hair loss, etc.