Acupoint Stimulation Improves Cognition Under Hypoxia
Not Applicable
Not yet recruiting
- Conditions
- Cognition
- Interventions
- Other: transcutaneous electrical acupoint stimulation
- Registration Number
- NCT06521632
- Lead Sponsor
- Zhihong LU
- Brief Summary
Cognitive impairment is common in people who suffer from hypoxia. Acupuncture and related techniques can be used to improve hypoxia and treat cognitive impairment. In this trial the effect of transcutaneous electrical acupoint stimulation on cognitive impairment in people under hypoxia will be investigated.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- Male
- Target Recruitment
- 50
Inclusion Criteria
- Male, age from 18 to 50 years
Exclusion Criteria
- cardiopulmonary dysfunction;
- History of severe respiratory, circulatory, digestive, blood, ear-nose-throat system diseases;
- A history of fever or respiratory infection within the last two weeks;
- Drinking alcohol or poor sleep within the last 24 hours
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description transcutaneous electrical acupoint stimulation transcutaneous electrical acupoint stimulation Electrodes are placed at acupoints and connected to the stimulators. Electrical stimulation is given for 2 hours
- Primary Outcome Measures
Name Time Method cognitive function measured by eye-tracking at 2 hours after hypoxia 2 hours after hypoxia cognitive function measured by eye-tracking at 1 hour after hypoxia 1 hour after hypoxia
- Secondary Outcome Measures
Name Time Method saturation of pulse oximetry starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes total sleep time on the first day after hypoxia the first day after hypoxia, in a total of 24 hours sleep efficiency(%) on the first day after hypoxia the first day after hypoxia, in a total of 24 hours sleep efficiency=total sleep time/total recording time
number of awake on the first day after hypoxia the first day after hypoxia, in a total of 24 hours time of awake on the first day after hypoxia the first day after hypoxia, in a total of 24 hours mean arterial blood pressure starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes Cerebral oxygen saturation starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes heart rate starting from 10 minutes before hypoxia to 2 hours after hypoxia, every 5 minutes for 2 hours and 10 minutes
Trial Locations
- Locations (1)
Xijing Hospital
🇨🇳Xi'an, Shaanxi, China