Reappearance of fungal infection and its effective treatment with oral antifungal drugs - a clinical trial.
- Conditions
- Health Condition 1: null- DermatophytosisHealth Condition 2: B359- Dermatophytosis, unspecified
- Registration Number
- CTRI/2017/09/009851
- Lead Sponsor
- Chinmay Kar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 155
(1) Adult patients (15-60 years) with recurrent tinea corporis, cruris or faciei or combinations of these attending our Dermatology OPD, will be the candidates of this study. Most of them present with an extensive form.
(2) They have a history of Cap Itraconazole intake (100mg twice daily for at least one month) without interruption and re-occurrence of similar form of tinea after stopping Itraconazole within a short period (one week to six weeks).
(3) They must have normal blood count, liver and renal function tests.
(4) Positive KOH smear on skin scraping.
(5) Regular follow up is possible and complied with to note the improvement and/or any other complications.
(1)Patients with Diabetes Mellitus or other immunocompromised disorders.
(2)Patients with H/O steroid or immunosuppressant medicines intake.
(3) Pregnant or lactating mother.
(4) Other family members will have chronic tinea infections.
(5) Patients with other form of tinea infection like tinea pedis, tinea manuum, tinea unguium etc.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinically free from signs and symptoms of superficial fungal infection and mycologically devoid of any fungal species on fungal culture.Timepoint: At the end of 1st, 2nd and 3rd month for each patient
- Secondary Outcome Measures
Name Time Method Clinically free but culture positivityTimepoint: End of 1st, 2nd and 3rd months.