The Effect of Galvanic Stimulation on vHIT and VEMP Tests

Not Applicable

Completed

• Conditions: Vestibular System Disorder

• Registration Number: NCT06123949
• Lead Sponsor: Istanbul Medipol University Hospital

Brief Summary

Introduction: Galvanic vestibular stimulation (GVS) is a well-established technique with a history spanning over a century, primarily used to manipulate the vestibular system. Recent interest has surged in its potential for understanding human vestibular function and aiding in functional recovery. GVS applies electrical currents to the mastoid region, modulating vestibular afferents, and induces specific effects based on the participant's posture and current polarity. While GVS's impact on the central nervous system and its potential to aid in functional recovery have been studied, its immediate effects on vestibular reflexes remain less explored.

Methods: In this study, thirty healthy adult participants underwent ocular and cervical vestibular evoked myogenic potential (VEMP) tests, as well as the velocity Head Impulse Test (vHIT) before and immediately after one hour of GVS application. Statistical analyses were performed to assess changes in VEMP and vHIT results.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-08-25
• Primary Completion: 2020-06-10
• Study Completion: 2020-09-10
• Study First Submitted: 2023-10-27
• Status Verified: 2023-11
• Study First Submitted QC: 2023-11-03
• Last Update Submitted: 2023-11-08
• Study First Posted: 2023-11-09
• Last Update Posted: 2023-11-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• No history of hearing loss and/or balance disorders
• No physical (neck) problems
• No history of psychological or neurological disorders
• Not using alcohol and/or vestibular suppressant drugs regularly
• Feeling balanced in daily life

Exclusion Criteria

• History of hearing loss and/or balance disorders
• Physical (neck) problems
• History of psychological or neurological disorders
• Using alcohol and/or vestibular suppressant drugs regularly

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Cervical Vestibuler Evoked Myogenic Potentials	5 months	Vestibular evoked myogenic potentials (VEMPs) are muscle reflexes that occur in response to high-intensity acoustic stimuli delivered to the ear. These responses can be easily recorded using surface electrodes placed on the sternocleidomastoid muscle (SCM) or near the inferior oblique muscle .
Ocular Vestibuler Evoked Myogenic Potentials	5 months	Vestibular evoked myogenic potentials (VEMPs) are muscle reflexes that occur in response to high-intensity acoustic stimuli delivered to the ear. Ocular VEMP (oVEMP) recorded from surface electrodes placed under the eyes.
Video Head Impulse Test	5 months	The vestibulo-ocular reflex (VOR) is responsible for stabilizing images on the fovea during head movement. The velocity Head Impulse Test (vHIT) battery is a standard test for measuring head and eye movements, enabling the calculation of the gain of eye speed. The vHIT system typically employs light goggles to monitor eye position through cameras, along with a gyroscope to measure angular head movements, facilitating the computation of VOR gain.

Trial Locations

Locations (1)

Istanbul Medipol University; 🇹🇷 Istanbul, Turkey