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Clinical Trials/NCT06123949
NCT06123949
Completed
Not Applicable

The Effect of Galvanic Stimulation on vHIT and VEMP Tests

Istanbul Medipol University Hospital1 site in 1 country30 target enrollmentAugust 25, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Vestibular System Disorder
Sponsor
Istanbul Medipol University Hospital
Enrollment
30
Locations
1
Primary Endpoint
Cervical Vestibuler Evoked Myogenic Potentials
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Introduction: Galvanic vestibular stimulation (GVS) is a well-established technique with a history spanning over a century, primarily used to manipulate the vestibular system. Recent interest has surged in its potential for understanding human vestibular function and aiding in functional recovery. GVS applies electrical currents to the mastoid region, modulating vestibular afferents, and induces specific effects based on the participant's posture and current polarity. While GVS's impact on the central nervous system and its potential to aid in functional recovery have been studied, its immediate effects on vestibular reflexes remain less explored.

Methods: In this study, thirty healthy adult participants underwent ocular and cervical vestibular evoked myogenic potential (VEMP) tests, as well as the velocity Head Impulse Test (vHIT) before and immediately after one hour of GVS application. Statistical analyses were performed to assess changes in VEMP and vHIT results.

Registry
clinicaltrials.gov
Start Date
August 25, 2019
End Date
September 10, 2020
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Istanbul Medipol University Hospital
Responsible Party
Principal Investigator
Principal Investigator

Berna Özge MUTLU

Principal Inverstigator

Istanbul Medipol University Hospital

Eligibility Criteria

Inclusion Criteria

  • No history of hearing loss and/or balance disorders
  • No physical (neck) problems
  • No history of psychological or neurological disorders
  • Not using alcohol and/or vestibular suppressant drugs regularly
  • Feeling balanced in daily life

Exclusion Criteria

  • History of hearing loss and/or balance disorders
  • Physical (neck) problems
  • History of psychological or neurological disorders
  • Using alcohol and/or vestibular suppressant drugs regularly

Outcomes

Primary Outcomes

Cervical Vestibuler Evoked Myogenic Potentials

Time Frame: 5 months

Vestibular evoked myogenic potentials (VEMPs) are muscle reflexes that occur in response to high-intensity acoustic stimuli delivered to the ear. These responses can be easily recorded using surface electrodes placed on the sternocleidomastoid muscle (SCM) or near the inferior oblique muscle .

Ocular Vestibuler Evoked Myogenic Potentials

Time Frame: 5 months

Vestibular evoked myogenic potentials (VEMPs) are muscle reflexes that occur in response to high-intensity acoustic stimuli delivered to the ear. Ocular VEMP (oVEMP) recorded from surface electrodes placed under the eyes.

Video Head Impulse Test

Time Frame: 5 months

The vestibulo-ocular reflex (VOR) is responsible for stabilizing images on the fovea during head movement. The velocity Head Impulse Test (vHIT) battery is a standard test for measuring head and eye movements, enabling the calculation of the gain of eye speed. The vHIT system typically employs light goggles to monitor eye position through cameras, along with a gyroscope to measure angular head movements, facilitating the computation of VOR gain.

Study Sites (1)

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