Anaemia and acid base parameters
- Conditions
- Health Condition 1: E611- Iron deficiencyHealth Condition 2: R710- Precipitous drop in hematocrit
- Registration Number
- CTRI/2022/02/039987
- Lead Sponsor
- AIIMS Raipur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1. Patients aged 18-65 years
2. Either Sex
3. Hb levels < 10.9 gm/dl
4. Belonging to ASA grade I & II
1. Patients aged <18 and >65 years
2. ASA grade III and above.
3. Patients with Hb > 10.9gm/dl.
4. Patients having any major illness or uncontrolled co-morbidity
5. Inability/unwillingness to give consent (e.g mental retardation etc)
6. All known causes of acid-base imbalances (confounding factors) such as seizures, neuromuscular disorders, reduced cardiac output, shock, PDA, heart failure, renal disease, renal failure, renal replacement therapy, gastrointestinal disease, dehydration, diarrhoea, vomiting, burns, supplementary feeds, asphyxia, hypoxemia, severe asthma, COPD, alcoholism, cancer, liver failure, abnormal LFT, carbon monoxide poisoning fever, sepsis, medicines such as salicylates, metformin, antiretrovirals, diuretics, ACEIâ??s, etc., low blood sugar, (hypoglycemia), exercising vigorously for a very long time, hypothermia, inborn error of metabolism, IV fluid therapy, diabetics, diabetic ketoacidosis poisonings, etc.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the relationship between a given Hb level below 10.9 g/dl and change in pH from the normal range i.e delta pH on a venous blood gas analysis.Timepoint: Outcome will be assessed co-relating the baseline value of Hb (less than 10.9g/dl) and ABG only.
- Secondary Outcome Measures
Name Time Method To determine the relationship between a given Hb level below 10.9 g/dl and change in HCO3, base excess and lactate level from the normal range i.e delta HCO3, delta base excess and delta lactate levels on a venous blood gas analysis.Timepoint: Outcome will be assessed co-relating the baseline value of Hb (less than 10.9g/dl) and ABG only.