Role of 3 Tesla Diffusion Weighted Magnetic Resonance Imaging (DW-MRI) for Diagnosis Bladder Cancer Grade and Stage

• Conditions: Magnetic Resonance Imaging; Bladder Cancer; Diagnoses Disease; Apparent Diffusion Coefficient

• Registration Number: NCT03138837
• Lead Sponsor: Mansoura University

Brief Summary

assess diagnostic performance of 3-Tesla DW-MRI in detecting and staging bladder cancer and potential role of the ADC value as a biomarker reflecting histological grade and stage.

Detailed Description

Not available

Study Timeline

• Status Verified: 2017-05
• Study First Submitted: 2017-05-01
• Study First Submitted QC: 2017-05-01
• Study First Posted: 2017-05-03
• Study Start: 2017-05-15
• Last Update Submitted: 2017-05-16
• Last Update Posted: 2017-05-17
• Primary Completion: 2018-05-15
• Study Completion: 2018-05-15

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 385

Inclusion Criteria

• Men and women 18 years or older
• Suspected by the out-patient flexible cystoscopy as Non-muscle invasive bladder cancer.
• Patient who will undergo radical cystectomy.
• Patient with history of allergy to iodinated contrast media

Exclusion Criteria

• Refuse to complete study requirements

• Patient with any of the following:

  1. Any metallic fragment or foreign body
  2. Coronary and peripheral artery stents
  3. Aortic stent graft
  4. Prosthetic heart valves and annuloplasty rings
  5. Cardiac pacemaker
  6. Implanted cardioverter-defibrillator (ICD)
  7. Retained trans venous pacemaker and defibrillator leads
  8. Cochlear, otologic, or other ear implant

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
assess the diagnostic performance of 3-T DW-MRI in detecting and staging bladder cancer	1 year	comparing the radiological diagnosis with the pathological specimen results

Trial Locations

Locations (1)

Urology and Nephrology Center; 🇪🇬 Mansoura, Aldakahlia, Egypt